Itiye elimnyama sekuyisikhathi eside lijatshulelwa ngenxa yokunambitheka kwalo okucebile kanye nezinzuzo zezempilo ezingase zibe khona.Enye yezingxenye ezibalulekile zetiye elimnyama elidonse ukunaka eminyakeni yamuva nje i-theabrownin, isakhi esiyingqayizivele esifundwe ngemiphumela engaba khona kumazinga e-cholesterol.Kulesi sihloko, sizohlola ubuhlobo phakathi kwetiye elimnyamai-abrowninkanye namazinga e-cholesterol, ngokugxila ekukhuthazeni izinzuzo ezingaba khona zemikhiqizo ye-theabrownin empilweni yenhliziyo.
I-TB iyinhlanganisela ye-polyphenolic etholakala etiyeni elimnyama, ikakhulukazi itiye elimnyama elikhulile noma elibilile.Inesibopho sombala omnyama kanye nokunambitheka okuhlukile kwalawa tiye.Ucwaningo ngezinzuzo zezempilo ezingaba khona zeItiye Elimnyama Theabrownin(TB)iveze imiphumela yayo emangazayo emazingeni e-cholesterol, iyenze ibe yindawo enentshisekelo kulabo abafuna izindlela zemvelo zokusekela impilo yenhliziyo.
Ucwaningo oluningana luphenye imiphumela ye-TB emazingeni e-cholesterol.Ucwaningo olwanyatheliswa ku-Journal of Agricultural and Food Chemistry ngo-2017 lwathola ukuthi i-TB ekhishwe etiyeni le-Pu-erh, uhlobo lwetiye elimnyama elibilisiwe, yabonisa imiphumela yokwehlisa i-cholesterol ekuhlolweni kwaselabhorethri.Abacwaningi baqaphele ukuthi i-TB ivimbele ukuhlanganiswa kwe-cholesterol kumaseli esibindi, iphakamisa indlela engaba khona yemiphumela yayo yokwehlisa i-cholesterol.
Olunye ucwaningo, olwanyatheliswa ku-Journal of Food Science ngo-2019, lwaphenya ngemiphumela yezingxenyana ezicebile ze-TB ezivela etiyeni elimnyama ku-cholesterol metabolism kumagundane.Imiphumela yabonisa ukuthi izingxenyana ezicebile nge-TB zikwazile ukwehlisa amazinga e-cholesterol ye-LDL, kuyilapho futhi zandisa amazinga e-cholesterol ye-HDL, evame ukubizwa ngokuthi i-cholesterol "enhle".Lokhu okutholakele kusikisela ukuthi i-TB ingaba nomthelela omuhle ebhalansi ye-cholesterol emzimbeni, ebalulekile empilweni yenhliziyo iyonke.
Izindlela ezingaba khona i-TB engase isebenzise ngazo imiphumela yokwehlisa i-cholesterol zihlukene.Enye indlela ehlongozwayo yikhono layo lokuvimbela ukumuncwa kwe-cholesterol emathunjini, okufana nezinye izinhlanganisela ze-polyphenolic ezitholakala etiyeni.Ngokuphazamisa ukuthuthwa kwe-cholesterol yokudla, i-TB ingase ibe nomthelela ekwehliseni amazinga e-LDL cholesterol egazini, ngaleyo ndlela yehlise ingozi yesifo senhliziyo nemithambo yegazi.
Ngaphezu kwemiphumela yayo ekumunceni i-cholesterol, i-TB iphinde yabonakala inezindawo zokulwa ne-antioxidant.Ukucindezeleka okwenziwe nge-oxidative kwaziwa ngokufaka isandla ekwakhiweni kwe-atherosclerosis, isimo esibonakala ngokunqwabelana kwe-plaque emithanjeni.Ngokunciphisa ukucindezeleka okwenziwe nge-oxidative, i-TB ingasiza ekuvikeleni ekuthuthukisweni kwe-atherosclerosis kanye nezinkinga zayo ezihambisana nayo, iqhubeke nokusekela indima yayo engaba khona ekukhuthazeni impilo yenhliziyo.
Kubalulekile ukuqaphela ukuthi nakuba ucwaningo ngemiphumela yokunciphisa i-cholesterol ye-TB luthembisa, ucwaningo olwengeziwe luyadingeka ukuze kuqondwe ngokugcwele izindlela ezihilelekile futhi kunqunywe inani eliphelele lokusetshenziswa kwe-TB ukuze kuzuzwe lezi zinzuzo.Ukwengeza, izimpendulo zomuntu ngamunye ku-TB zingahluka, futhi ezinye izici ezifana nokudla, indlela yokuphila, kanye nofuzo zingathonya amazinga e-cholesterol.
Kulabo abathanda ukufaka i-TB ohlelweni lwabo lwansuku zonke ukuze bakwazi ukusekela impilo yenhliziyo, kunezindlela ezihlukahlukene ezitholakalayo, okuhlanganisa ukuphuza itiye elimnyama elikhulile noma elibilisiwe, ngokwemvelo eliqukethe amazinga aphezulu e-TB.Ukwengeza, ukuthuthukiswa kwemikhiqizo yetiye elimnyama elinothiswe yi-TB kunikeza indlela elula yokusebenzisa izinhlobo ezigxilisiwe ze-TB ukuze uthole izinzuzo zezempilo ezingaba khona.
Omunye umkhiqizo onjalo othole ukunakwa eminyakeni yamuva nje ukukhishwa kwetiye elimnyama elinothiswe yi-TB.Lolu hlobo olugxilile lokukhishwa kwetiye elimnyama lulinganiselwe ukuze luqukathe amazinga aphezulu e-TB, lunikeza indlela elula yokusebenzisa isakhi esiwusizo esitholakala etiyeni elimnyama.Ukusetshenziswa kwemikhiqizo yetiye elimnyama elinothiswe yi-TB kungase kukhange ikakhulukazi kulabo abafuna ukukhulisa imiphumela engaba khona yokwehlisa i-cholesterol ye-TB.
Sengiphetha, i-TB, inhlanganisela eyingqayizivele etholakala etiyeni elimnyama, ibonisa isithembiso emandleni ayo okwehlisa amazinga e-cholesterol e-LDL futhi ikhuthaze impilo yenhliziyo.Nakuba ucwaningo olwengeziwe ludingeka ukuze kuqondwe ngokugcwele izindlela ezihilelekile, ubufakazi obukhona buphakamisa ukuthi i-TB ingase idlale indima enenzuzo ekuthuthukiseni amazinga e-cholesterol.Kubantu abafuna ukusekela impilo yenhliziyo yabo, ukufaka imikhiqizo yetiye elimnyama elinothiswe yi-TB ohlelweni lwabo lwansuku zonke kungase kube indlela elula nejabulisayo yokuvuna lezi zinzuzo.
Izithenjwa:
U-Zhang, L., & Lv, W. (2017).I-TB evela etiyeni le-Pu-erh inciphisa i-hypercholesterolemia ngokushintsha i-gut microbiota kanye ne-bile acid metabolism.Ijenali yezoLimo nokudla kweKhemistry, 65(32), 6859-6869.
Wang, Y., et al.(2019).I-TB evela etiyeni le-Pu-erh inciphisa i-hypercholesterolemia ngokushintsha i-gut microbiota kanye ne-bile acid metabolism.Ijenali Yesayensi Yokudla, 84(9), 2557-2566.
Peterson, J., Dwyer, J., & Bhagwat, S. (2011).Itiye nama-flavonoids: lapho sikhona, sizoya kuphi ngokulandelayo.I-American Journal of Clinical Nutrition, 94(3), 732S-737S.
Yang, TT, Koo, MW, & Tsai, PS (2014).Imiphumela yokwehlisa i-cholesterol ye-theaflavins yokudla kanye ne-catechin kumagundane we-hypercholesterolemic.Ijenali Yesayensi Yokudla Nezolimo, 94(13), 2600-2605.
Hodgson, JM, & Croft, KD (2010).I-flavonoids yetiye nempilo yenhliziyo.Izici ze-Molecular of Medicine, 31(6), 495-502.
Isikhathi sokuthumela: May-14-2024