IZINDABA - ARARInnosides are ginsenosides: umngcele olandelayo emthini we-herbal

I. Isingeniso

Emhlabeni we-herbal umuthi, ukufuna amakhambi emvelo ngezinzuzo zezempilo ezinamandla kuholele ekutholweni kwe-ginsenosides engavamile. Kususelwa ezimpandeni zePanax Ginseng, lezi zinhlanganisela ezihlukile ziye zavusa isithakazelo esibalulekile emiphakathini yesayensi neyazokwelapha ngenxa yezakhiwo zazo ezithembisayo ezithembisayo. Njengoba abaphenyi bahlaselwa ekujuleni kwe-Ginsenosides engavamile, amandla abo okuguqula umuthi wamakhambi avele ngokwengeziwe.

II. Ukwembulela Amagugu Afihliwe

Ama-ginsenosides, owaziwa nangokuthi ama-saponins e-ginseng, yizinto eziyisisekelo ze-bioactive atholakala eGicnseng. Ngenkathi ama-ginsenosides endabuko anjenge-RG1, RC, Rd, Re, Rb1, kanye ne-RB2 bafundwe kakhulu, manje sekuvele kuguqulwe abalingani babo abangajwayelekile. Ama-ginsenosides angavamile, afaka i-RG3, RK1, kanye ne-RG5, anakekela imiphumela yawo ehlukahlukene futhi enamandla.
Lezi ginsinsides ezingavamile zibonakaliswa yizinhlaka zazo ezihlukile zamakhemikhali nemisebenzi yemvelo ehlukile. Ngokungafani nabalingani babo abajwayelekile, ama-ginsenosides angavamile akhombisa i-cholesterol-efana ne-skeleton enamakhambi afana ne-trans-ring-ring enezinkomo ezahlukahlukene, efaka isandla ezizakhisweni zazo zokwelapha ezihlukile.

Izakhiwo zamakhemikhali:
Ama-ginsenosides angavamile abonakala ngesikhumba esiyingqayizivele se-steroid esinezinhlelo zokusebenza ezikhethekile ze-hydroxyl, glycosyl, namanye amaqembu asebenzayo. Lesi sakhiwo samakhemikhali esihlukile sibabeka ngaphandle kwe-ginsenosides evamile futhi badlala indima ebaluleke kakhulu emisebenzini yabo yemvelo yemvelo. Ukuba khona kwamaqembu anoshukela amaningi namaqembu e-hydroxyl ngaphakathi kohlaka lwawo lwamakhemikhali kunomthelela ekubumbeni kwabo, ukuqina, kanye nokusebenzisana okunama-courser okuhlosiwe.

Ukwehlukahlukahluka kwesakhiwo kwe-ginsenosides engavamile kuyisici esibalulekile emandleni abo emithi, njengoba kuthonya amandla abo okusebenzisana nemigomo ehlukahlukene yamamolekyula emzimbeni. Lesi sakhiwo esiyinkimbinkimbi sivumela ama-ginsenosides angavamile ukuba asebenzise imali ehlukahlukene yemiphumela yemvelo, okwenza babe ngabamele izicelo zezokwelapha.

Imisebenzi Ehlukile Yezemfundo:
Ama-ginsenosides angavamile akhombisa ububanzi bemisebenzi yemvelo ebabeka ngaphandle kwabalingani babo abajwayelekile. Lezi zinhlanganisela zikhonjiswe ukuthi zinokulwa nokuvuvukala, i-antioxidant, i-anti-cancer, ama-neuroproptectic, kanye nezakhiwo zezinhliziyo, phakathi kwabanye. Amandla abo okuguqula izindlela zokusayina amaselula, alawule inkulumo yofuzo, futhi ahlanganyele namaprotheni athile anikela ngemiphumela yawo ehlukahlukene yemvelo.

Isibonelo, ama-ginsenosides angavamile abonise imisebenzi yokulwa nomdlavuza enamandla, okubandakanya ukuvinjwa kwe-apoptosis yeseli, ukungeniswa kwe-apoptosis, kanye nokucindezela kwe-angiogeneis. Ngokwengeziwe, imiphumela yabo yezinzwa ibonise isithembiso ekunciphiseni izimo ze-neurodegenerative ngokuthuthukisa ukusinda kwe-neuronal, ukunciphisa ukucindezelwa kwe-oxidative, kanye nokushintshanisa kwe-neurotransmitter umsebenzi.

Izinhlaka zamakhemikhali eziyingqayizivele ze-ginsenosides ezingavamile zize zikwazi ukusebenzisana nezinjongo ezithile ze-molefanelar, ezinjenge-receptors, enzyme, kanye nokusayina ama-molecule, okuholela ekushintsheni kwezinqubo ezahlukahlukene zomzimba. Lo msebenzi oqondisiwe uvumela ama-ginsenosides angavamile ukuba asebenzise imiphumela ephakeme emsebenzini wamaselula, abenze babe yimpahla ebalulekile ekuthuthukisweni kokungenelela kokwelashwa kwenoveli.

Ngamafuphi, izinhlaka zamakhemikhali ezihlukile nemisebenzi yemvelo ehlukene ye-ginsenosides engavamile ukubabeka njengezakhi ezibalulekile endaweni yokwelapha amakhambi. Ukucushwa kwabo okuhlukile kwamamolekyuli kanye nemiphumela emihle emikhemeni yagcizelela amandla abo okufaka isandla ekwakhiweni kwezindlela zokwelapha ezintsha zezimo eziningi zezempilo. Njengoba ucwaningo luqhubeka luveza ubunzima bezinkampani ezingavelele ama-ginsenosides angavamile, ukubaluleka kwazo ekubumbeni ikusasa lemithi yemvelo kuqala ngokwengeziwe.

III. Ukuhlola Amandla Ekhemisi

Amandla okhemisi we-ginsenosides engavamile kuyisihloko socwaningo olujulile nokuhlola. Ucwaningo seluveze ukuthi lezi zinhlanganisela zinezinhla ezibanzi ze-bioactivities, kufaka phakathi ukuvuvukala kokuvuvukala, i-antioxidant, umdlavuza womdlavuza, imiphumela ye-neuropropective, kanye nemiphumela yezinhliziyo. Amandla abo okushintsha izindlela ezahlukahlukene zokusayina amaselula kanye nama-molefanelar okuhlosiwe abenza bathembise abazokwethula ama-noverave.

Enye yezindawo eziphoqayo zocwaningo iyizakhiwo ze-anticancer ze-ginsenosides engavamile. Lezi zinhlanganisela zikhombisile imiphumela ebalulekile elwa nokwanda futhi i-pro-apoptotic emigqeni ehlukahlukene yomdlavuza we-cell cell, enikeza izindlela ezingaba khona zokwakhiwa kwezinye izindlela zomdlavuza. Ngokwengeziwe, imiphumela yabo yobunqunu iye yaveza inzalo ezisetshenzisweni zazo ezingaba khona zezifo ze-neurodegenerative ezinjenge-Alzheimer's and Parkinson's.

Ukubopha amandla okulapha
Njengoba umphakathi wesayensi uqhubeka uvule amandla okulapha ama-ginsenosides angavamile, umbuzo wokuhlanganisa izinzuzo zabo zempilo yabantu. Ochwepheshe bezempilo bancoma ukuqeda izimpande ze-ginseng eziluhlaza noma i-ginseng ekhishwe ukuze uthenge ezinhlolweni ezingaba khona zalezi zinhlaka. Kuphakanyiswa ukuthi uqale ngemithamo ephansi futhi ukhuphule kancane kancane ngokuhamba kwesikhathi ukukala ukubekezelelana komuntu ngamunye nokuphendula.
Lapho ubheka ukusekelwa kwe-ginseng, kubalulekile ukuze ukhethe ama-extracts ajwayelekile aqukethe amaphesenti athile e-ginsenosides ephelele. Lokhu kuqinisekisa i-potency engaguquki kanye nokusebenza ngempumelelo, okuvumela abantu ukuthi bandise ukumuncwa kanye nemiphumela yokwelapha ye-ginsenosides engavamile.

IZINSELELE NOKUFUNDA
Ngenkathi amandla e-ginsenosides angavamile emithini yamakhambi ethembisa, kubalulekile ukubhekana nezinselelo nokucatshangelwa okungaba khona. Ukusetshenziswa kwesikhathi eside kwePanax Ginseng, ikakhulukazi emithanjeni ephezulu, kungaholela emiphumeleni emibi efana nokuqwasha, futhi kwezinye izikhathi, ukusabela okunamandla komzimba kanye nomonakalo wesibindi. Ngakho-ke, kubalulekile ukuthi kuqashelwe ukuqaphela futhi kufune ukuholwa ngochwepheshe lapho kufaka imikhiqizo ye-ginseng emthonjeni womuntu.

Ubheke phambili
Ama-ginsenosides angavamile amele umngcele omusha emthini wamakhambi, enikeza ingcebo yamathuba okubhekana nezimo ezahlukahlukene zezempilo kanye nokwenza ngcono inhlala-kahle. Njengoba ucwaningo luyaqhubeka nokukhanyisela ngezokwelapha kanye namathuba okulashwa alapha, ukuhlanganiswa kwe-ginsenosides engavamile kuma-phynate Healtices ezempilo aphethe ngekusasa lemithi yemvelo.

Sengiphetha, ukuhlola ama-ginsenosides angavamile kuphambana nesahluko esijabulisayo ekuphendukeni kwemithi ye-herbal. Ngezinhlaka zazo ezihlukile zamakhemikhali nemisebenzi yezemvelo ehlukene, lezi zinhlaka zilungele ukuchaza kabusha isimo semvelo samakhambi emvelo futhi sinikele ekuthuthukisweni kwempilo nokuphila okuhle.

Njengoba singena kulo mngcele omusha omusha, amathuba okuba ama-ginsenosides angavamile ukwakha ikusasa lomuthi wamakhambi kuyithemba elinamandla, enikeza ithemba ngezindlela ezintsha zezempilo nokuphulukisa.