Izindaba - Yiziphi izinzuzo zezempilo zikakolweni we-germac ekhipha i-spermidine?

I. Isingeniso

Yini ukolweni i-shadot ekhipha i-spermidine6

I-Wheat Gemal Khipha i-Spermidine, i-polyamine yemvelo etholakala ekudleni okuhlukahlukene, bekulokhu kunesihloko socwaningo olunzulu ngenxa yezinzuzo zalo zezempilo ezingaba khona kanye neqhaza ekusekeleni izinqubo zeselula. Nakhu ukubheka okuningiliziwe izinzuzo zezempilo ezihambisana ne-Spermidine:

II. Yiziphi izinzuzo zezempilo zikakolweni we-phesheya zikhipha i-spermidine

Imiphumela yokulwa nokuguga:Isidoda sixhunyaniswe nemiphumela yokulwa nokuguga, ngoba sibandakanyeka ekuqondisweni kwe-autophagy, inqubo yamaselula esiza ukususa izingxenye ezilimele ezilimele futhi ikhuthaze impilo yeselula. Le nqubo ihlotshaniswa nokuvunyelwa kwezinsimbi ezilimele nezinhlanganisela zamaprotheni, ezinganqwabelana ngeminyaka nokufaka isandla ezifweni ezahlukahlukene. Ngokukhuthaza i-autophagy, i-spermidine ingasiza ukulondolozwa kwezempilo kanye nokusebenza kwamaselula, okungezelela ukunweba isikhathi sokuphila samaseli nokubambezela ukuqala kwezifo ezihlobene nobudala.

Impilo yenhliziyo:Isidoda sikhombise amathuba okuthuthukisa impilo yenhliziyo. Kutholakele ukwehlisa ukuthuthukiswa kwe-atherossclerosis ngokunciphisa ukuvuvukala kanye nokwenza ngcono iseli (mitochondria) ukusebenza. Ngaphezu kwalokho, i-spermidine inganciphisa ukwakheka kwama-cloot egazi (ukuhlanganiswa kwe-platelalet) futhi kuthuthukise umphumela ojwayelekile wokuhlabelela wamaseli wokufaka imithambo yegazi, kufaka isandla ekutholeni umfutho wegazi futhi kuvimbele ukwehluleka kwenhliziyo.

I-NeuropTotection:I-SPRIMIDIE ingavikele ekulimaleni kwezinzwa ebuchosheni, ngokuvimbela izifo ze-neurologic ezifana nama-Alzheimer's and Parkinson's. Kuboniswe ukusiza ukunciphisa ukunciphisa ukuqwashisa ngokomqondo, inkumbulo, kanye nokulimazeka okusebenzayo okuhlotshaniswa nokuguga.

Umthethonqubo we-Blood Sugar:Isidoda sikhonjiswe ukuthuthukisa amandla omzimba okusebenzisa i-insulin futhi yehlise amazinga kashukela wegazi, okungazuzisa ukuphathwa kwezifo sikashukela.

Impilo yethambo:Isidoda singakhulisa amandla amathambo futhi sivikele ukulahleka kwamathambo, okwenza kube yinzuzo ekuvikeleni i-osteoporosis. Kungavimbela nokulahleka okuhlobene nobudala kwemisipha yamathambo futhi kuthuthukise ukusebenza kwemisipha.

Ukuxhaswa kwamasosha omzimba:I-SPRIDIDINE ibonise izakhiwo zokulwa nokuvuvukala futhi ingasiza ekunciphiseni ubulukhuni besifo samathumbu ukuvuvukala. Kuboniswe futhi ukuthuthukisa ukusebenza kwamangqamuzana omzimba kusuka kubanikeli babantu asebekhulile futhi kunciphise ukusakazwa kwamagciwane, kuphakamisa indima ekuphakamiseni amasosha omzimba abhekene nezinsongo zangaphandle.

Imiphumela ye-Epigenetic:Isidoda singathinta isimo se-epigenetic ngokunciphisa i-histone acetylation kanye nethonya isimo se-acetylation samaprotheni amaningi we-cytoplasmic. Lokhu kungaba nomthelela ezvelno gene kanye nezinqubo zeselula, kufaka phakathi i-autophagy.

Umsebenzi we-Mitochondrial:Isidoda sixhunyaniswe nokwenza ngcono umsebenzi we-mitochondrial, okubaluleke kakhulu ukukhiqizwa kwamandla ngaphakathi kwamaseli. Kungase kuvuse ukukhiqizwa kwe-mitchondria entsha futhi kuthuthukise imvume yokulimala kwalabo abalimele ngenqubo ebizwa ngokuthi yi-mitophagy.

Ekuphetheni, ukolweni we-germ ekhipha i-spermidine ehlukahlukene kunikezela ngezinzuzo ezingaba khona zezempilo, kusuka emiphumeleni yokulwa nokuguga ukusekela umsebenzi wokuqonda, impilo yenhliziyo, nokuxhaswa kwamasosha omzimba. Kodwa-ke, kubalulekile ukuqaphela ukuthi ngenkathi i-spermidine iyingxenye yemvelo etholakala ekudleni okuningi futhi ngokuvamile ibekezelelwa kahle, kuhlale kungcono ukuthintana nochwepheshe wezokunakekelwa kwempilo ngaphambi kokudla noma ngesengezo regimen.