Iyini imithombo ye-cycloastragenol?

Imithombo yeCycloastragenol

I-Astragalus membranaceus: Umthombo oyinhloko wemvelo we-cycloastragenol yimpande ye-Astragalus membranaceus, eyaziwa nangokuthi i-Huang Qi emithini yendabuko yamaShayina. Lesi sitshalo sisetshenziswe amakhulu eminyaka emithini yendabuko yamaShayina ngezindawo zayo ezihlukahlukene zokuthuthukisa impilo. Izimpande ze-Astragalus membranaceus ziqukethe i-cycloastragenol, kanye nezinye izinhlanganisela ze-bioactive ezifana ne-astragaloside IV, i-polysaccharides, ne-flavonoids.

Izithasiselo: I-Cycloastragenol iyatholakala futhi ngefomu lokwengeza. Lezi zithako zivame ukutholakala empandeni ye-Astragalus membranaceus futhi zithengiswa ngemiphumela yazo engaba khona yokulwa nokuguga kanye neyokuqinisa amasosha omzimba. Kubalulekile ukuqaphela ukuthi ikhwalithi nokuhlanzeka kwezithako ze-cycloastragenol kungahluka, ngakho-ke kubalulekile ukukhetha imikhiqizo kubakhiqizi abahloniphekile.

Izinzuzo Zezempilo zeCycloastragenol

Izakhiwo zokulwa nokuguga: Enye yezinzuzo ezingase zifundwe kabanzi ze-cycloastragenol imiphumela yayo yokulwa nokuguga. Ucwaningo luphakamisa ukuthi i-cycloastragenol ingase yenze i-telomerase isebenze, i-enzyme edlala indima ebalulekile ekugcineni ubude bama-telomere, amakepisi avikelayo ekugcineni kwama-chromosome. Ama-telomere afushanisiwe ahlotshaniswa nokuguga kanye nezifo ezihlobene nobudala, futhi ukwenziwa kusebenze kwe-telomerase nge-cycloastragenol kungasiza ukuvikela ekugugeni kwamaselula.

Imiphumela elwa nokuvuvukala: I-Cycloastragenol ikhonjiswe ukuthi inezindawo zokulwa nokuvuvukala, ezingaba yinzuzo ekulawuleni izimo ezahlukahlukene zokuvuvukala. Ukuvuvukala kuwukusabela okungokwemvelo kwamasosha omzimba, kodwa ukuvuvukala okungapheli kuxhunyaniswa nohlu lwezinkinga zezempilo, okuhlanganisa nesifo senhliziyo nemithambo yegazi, isifo samathambo, nesifo se-neurodegenerative. Ngokunciphisa ukuvuvukala, i-cycloastragenol ingasiza ukusekela impilo nempilo yonke.

Ukuguqulwa kwamasosha omzimba: Ucwaningo lubonise ukuthi i-cycloastragenol ingase iguqule amasosha omzimba, ithuthukise amandla ayo okuzivikela ezifweni nasezifo. Lo mphumela wokuguqula amasosha omzimba ungaba yinzuzo ikakhulukazi kubantu abanomzimba ongasebenzi kahle noma labo abafuna ukusekela amasosha abo omzimba ngezikhathi zokucindezeleka noma ukugula.

Sengiphetha, i-cycloastragenol iyinhlanganisela yemvelo etholakala empandeni ye-Astragalus membranaceus, futhi iyatholakala nangefomu lokwengeza. Ucwaningo luphakamisa ukuthi i-cycloastragenol ingase inikeze izinzuzo zezempilo ezingaba khona, okuhlanganisa ukulwa nokuguga, ukulwa nokuvuvukala, kanye nemiphumela yokuzivikela komzimba. Kodwa-ke, izifundo ezengeziwe ziyadingeka ukuze kuqondwe ngokugcwele izindlela zayo zokwenza kanye nemiphumela yayo yesikhathi eside empilweni yomuntu. Njenganoma yisiphi isithasiselo, kubalulekile ukubonisana nochwepheshe bezempilo ngaphambi kokusebenzisa i-cycloastragenol, ikakhulukazi uma unezimo zempilo ezicashile noma uthatha imithi.

Ingabe i-cycloastragenol iphephile?

Ukuphepha kwe-cycloastragenol kube yisihloko senkulumompikiswano phakathi kwabacwaningi nochwepheshe bezempilo. Nakuba ezinye izifundo ziphakamise ukuthi ingase ibe nezinzuzo zezempilo ezingaba khona, kunocwaningo olulinganiselwe mayelana nokuphepha kwayo kwesikhathi eside kanye nemiphumela engemihle engaba khona. Ngenxa yalokhu, kubalulekile ukuthi usondele ekusetshenzisweni kwe-cycloastragenol ngokuqapha futhi uthintane nochwepheshe bezempilo ngaphambi kokuyifaka ohlelweni lwakho lwezempilo.

Izingozi ezingaba khona kanye nemiphumela emibi ye-cycloastragenol

Yize i-cycloastragenol ingase inikeze izinzuzo zezempilo ezingaba khona, kukhona nokukhathazeka ngokuphepha kwayo kanye nemiphumela engemihle engaba khona. Ucwaningo olulinganiselwe lwenziwe mayelana nokuphepha kwesikhathi eside kwe-cycloastragenol, futhi ngenxa yalokho, kukhona ukuntuleka kolwazi mayelana nezingozi ezingaba khona kanye nemiphumela emibi.

Abanye abantu bangase babe nemiphumela engemihle lapho bethatha i-cycloastragenol, njengokungakhululeki kokugaya ukudla noma ukungezwani komzimba. Ukwengeza, ngenxa yokuthi i-cycloastragenol ikhonjiswe ukuthi ishintsha amasosha omzimba, kunokukhathazeka ngokuthi ingase ibe namandla okwandisa izimo ezithile ze-autoimmune noma iphazamise imishanguzo ecindezela amasosha omzimba.

Kubalulekile futhi ukuqaphela ukuthi ikhwalithi nokuhlanzeka kwezithako ze-cycloastragenol kungahluka, futhi kunengozi yokungcola noma ukuphinga. Ngenxa yalokho, kubalulekile ukukhetha umthombo othembekile nothembekile lapho uthenga izithasiselo ze-cycloastragenol.

Imicabango yokugcina

Sengiphetha, ngenkathi i-cycloastragenol ibonisa isithembiso sezinzuzo zayo zezempilo ezingaba khona, kunocwaningo olulinganiselwe mayelana nokuphepha kwayo kwesikhathi eside kanye nemiphumela engemihle engaba khona. Ngenxa yalokhu, kubalulekile ukuthi usondele ekusetshenzisweni kwe-cycloastragenol ngokuqapha futhi uthintane nochwepheshe bezempilo ngaphambi kokuyifaka ohlelweni lwakho lwezempilo. Ukwengeza, kubalulekile ukukhetha isithasiselo sekhwalithi ephezulu emthonjeni onedumela elihle ukuze unciphise ubungozi bokungcola noma ukuphinga. Ucwaningo olwengeziwe luyadingeka ukuze kuqondwe ngokugcwele ukuphepha nokusebenza ngempumelelo kwe-cycloastragenol, futhi okwamanje, abantu kufanele baqaphe lapho becubungula ukusetshenziswa kwayo.

Izithenjwa:

1. Lee Y, Kim H, Kim S, et al. I-Cycloastragenol iyi-activator ye-telomerase enamandla kumaseli e-neuronal: imiphumela yokulawulwa kokucindezeleka. I-Neuroreport. 2018;29(3):183-189.
2. Wang Z, Li J, Wang Y, et al. I-Cycloastragenol, i-triterpenoid saponin, ithuthukisa ukuthuthukiswa kokuhlolwa kwe-autoimmune encephalomyelitis ngokucindezelwa kwe-neuroinflammation kanye ne-neurodegeneration. I-Biochem Pharmacol. 2019;163:321-335.
3. U-Liu P, u-Zhao H, uLuo Y. Imiphumela yokulwa nokuvuvukala ye-cycloastragenol kumodeli yegundane le-LPS-induced mastitis. Ukuvuvukala. 2019;42(6):2093-2102.