Ukuqalisa
Uhlobo lwezimbali, Ikhambi elidumile le-herbal, lisetshenziselwe amakhulu eminyaka emithini yendabuko ngezinzuzo zayo zezempilo. Enye yezinto ezibalulekile ze-bikoactivent of ginseng yi-ginsenosides, okukholelwa ukuthi inesibopho sezakhiwo zayo zokwelapha eziningi. Kulesi sihloko, sizohlola iphesenti le-ginsenosides e-ginseng, ukubaluleka kwazo, kanye nemiphumela yekhwalithi kanye nokusebenza kahle kwemikhiqizo ye-ginseng.
Ama-ginsenosides: amakhompiyutha asebenzayo e-ginseng
Ama-ginsenosides ayi-class of compound yemvelo etholakala ezimpandeni zePanax Ginseng Plant, kanye nakwezinye izinhlobo ezihlobene nePanax Genus. Lezi zinhlanganisela ezi-bioactive zihlukile ku-ginseng futhi zinesibopho semiphumela eminingi yayo yemithi. Ama-ginsenosides angama-triterpene saponins, abonakala ngezinhlaka zawo ezihlukene zamakhemikhali nemisebenzi yemvelo.
Amaphesenti ama-ginsenosides e-ginseng angahluka ngokuya ngezinto ezifana nezinhlobo ze-ginseng, iminyaka yesitshalo, izimo ezikhulayo, kanye nendlela yokukhishwa. Ngokuvamile, okuqukethwe okuphelele kwe-ginsenoside kusetshenziswa njengesilinganiso sekhwalithi kanye ne-potency yemikhiqizo ye-ginseng, ngoba kubonisa ukugcwaliswa kwezindawo ezisebenzayo ezibhekele imiphumela yayo yokwelapha.
Amaphesenti ama-ginsenosides e-ginseng
Amaphesenti ama-ginsenosides e-ginseng angasukela ku-2% kuye ku-6% empandeni, ngokuhlukahluka ngokuya ngezinhlobo ezithile ezisetshenzisiwe kanye nengxenye yesitshalo esisetshenzisiwe. Isibonelo, i-Korean Red Ginseng, elungiselelwe ngokunuka futhi yomisa izimpande ze-ginseng, imvamisa ingamaphesenti aphezulu e-ginsenosides ngokuqhathaniswa ne-ginseng eluhlaza. Ngaphezu kwalokho, ukugcwaliseka kwama-ginsenosides ngazinye ngaphakathi kokuqukethwe okuphelele kwe-ginsenoside nakho kungahlukahluka, ngohlobo oluthile lwe-ginsenosides luningi kunabanye.
Amaphesenti ama-ginsenosides ajwayele ukusetshenziswa njengophawu lwekhwalithi kanye ne-potency yemikhiqizo ye-ginseng. Amaphesenti aphezulu ama-ginsenosides ngokuvamile ahlotshaniswa namakhono amakhulu okulapha, njengoba lezi zinhlaka kukholakala ukuthi zibhekele imiphumela yemithi ye-ginseng, kufaka phakathi i-admogenic, nokuvuvukala okuguquguqukayo.
Ukubaluleka kokuqukethwe kwe-ginsenoside
Amaphesenti ama-ginsenosides eGinsen aqakathekile ngezizathu eziningana. Okokuqala, isebenza njengesilinganiso sekhwalithi nobuqiniso bemikhiqizo ye-ginseng. Amaphesenti aphezulu ama-ginsenosides akhombisa ukugcwaliseka okuphezulu kwamakhompiyutha asebenzayo, okufiseleka ukufeza imiphumela yokwelapha efiselekayo. Ngakho-ke, abathengi nabakhiqizi bavame ukubheka imikhiqizo ye-ginseng enokuqukethwe okuphezulu kwe-ginsenoside ukuqinisekisa ukusebenza kwayo.
Okwesibili, iphesenti lama-ginsenosides lingathonya ama-bioavailability kanye nama-pharmacokinetics emikhiqizo ye-ginseng. Ukugxila okuphezulu kwama-ginsenosides kungaholela ekutholeni okukhulu nasekusatshalalisweni kwalezi zinhlanganisela emzimbeni, ngokuqinisa imiphumela yabo yokwelapha. Lokhu kubaluleke kakhulu ekuthathweni kwama-ginseng kanye namalungiselelo amakhambi, lapho ama-bioavaliability of ginsenosides angathinta ukusebenza kwawo kwemitholampilo.
Imiphumela yokulawulwa kwekhwalithi nokuma okujwayelekile
Amaphesenti ama-ginsenosides eGinsen anemiphumela yokulawulwa kwekhwalithi kanye nokuma okumisiwe kwemikhiqizo ye-ginseng. Echaza ukukhishwa okuqukethwe kwe-ginseng okususelwa kokuqukethwe kwabo kwe-ginsenoside kuvumela ukungaguquguquki ekwakhiweni nasekusebenzeni kwamalungiselelo e-ginseng, ukuqinisekisa ukuthi abathengi bathola umkhiqizo othembekile nophumelelayo.
Izindlela zokulawula ezisezingeni eliphakeme, ezinjenge-chromatography ephezulu ye-chromatography (HPLC) ne-mass spectrometry, zivame ukusetshenziswa ukunciphisa okuqukethwe kwe-ginsenoside emikhiqizweni ye-ginseng. Lezi zinqubo zokuhlaziya zivumela ukunqunywa okunembile kwamaphesenti ama-ginsenosides, kanye nokuhlonza kanye nokuqanjwa kwama-ginsenosides ngamanye akhona endaweni ekhishwe.
Ngaphezu kwalokho, iziphathimandla ezilawulayo nezinhlangano zezimboni zingasungula imihlahlandlela kanye nokucaciswa kokuqukethwe kwe-ginsenoside yemikhiqizo ye-ginseng ukuqinisekisa ikhwalithi nokuphepha kwabo. Lezi zindinganiso zisiza ukuvikela abathengi kusuka kumikhiqizo ephithizelwe noma engaphansi ye-ginseng futhi kukhuthaza ukucaca kanye nokuziphendulela embonini ye-ginseng.
Ukugcina
Ekuphetheni, iphesenti le-ginsenosides eGinsen liyisiqalo esibalulekile sekhwalithi yalo, i-potency, kanye nokusebenza kwezokwelapha. Amaphesenti aphezulu ama-ginsenosides ngokuvamile ahlotshaniswa nemiphumela emikhulu yemithi, okwenza badinge ukuba abathengi bafune izinzuzo zezempilo ze-ginseng. Emisakalo imikhiqizo ye-ginseng ngokususelwa kokuqukethwe kwabo kwe-ginsenoside kanye nokusebenzisa izindlela zokulawula ikhwalithi kubalulekile ukuze kuqinisekiswe ukungaguquguquki nokwethenjwa kwamalungiselelo e-ginseng. Njengoba ucwaningo luqhubeka nokwambula amandla okulapha ama-ginsenosides, amaphesenti alezi zinhlaka ze-bioactive eGiyon zizohlala ziyisici esibalulekile ekuhlolweni nasekusetshenzisweni kwalolu khambi lwekhambi elibalulekile.
Ukunqubekela phambili
UTele, njengoba, Wu, Ja, & Yuan, CS (1999). I-ginseng pharmacology: izindawo eziningi nezenzo eziningi. I-Biochemical Pharmacology, 58 (11), 1685-1693.
I-Baeg, ih, & ngakho-ke, sh (2013). Imakethe ye-Ginseng yezwe kanye ne-ginseng (Korea). Ijenali yocwaningo lwe-ginseng, 37 (1), 1-7.
Christensen, LP (2009). Ama-Ginnsenosides: Chemistry, Biosynthesis, ukuhlaziya, nemiphumela engaba khona yezempilo. Intuthuko ekucwaningweni kokudla nokudla okunempilo, 55, 1-99.
UKim, JH (2012). Ukusetshenziswa kokhemisi kanye nezokwelapha zePanax Ginseng kanye ne-ginsenosides: isibuyekezo sokusetshenziswa ezifweni zenhliziyo. Ijenali yocwaningo lwe-ginseng, 36 (1), 16-26.
UVuksan, V., Sievenpiper, JL, & Koo, vy (2008). I-American Ginseng (iPanax Quinquefolius L) inciphisa i-glycemia yasemuva kwezihloko ze-nondiabetic nezifundo ngohlobo 2 sikashukela ushukela mellitus. Archives of Internal Medicine, 168 (19), 2044-2046.
Isikhathi sePosi: APR-17-2024
