Ingakanani Iphesenti le-Ginseng i-Ginsenosides?

Isingeniso
I-Ginseng, ikhambi lekhambi elidumile, selisetshenziswe amakhulu eminyaka emithini yendabuko ngenxa yezinzuzo zalo zezempilo ezingaba khona. Enye yezingxenye ezibalulekile ze-bioactive ye-ginseng i-ginsenosides, okukholakala ukuthi inesibopho sezakhi zayo eziningi zokwelapha. Kulesi sihloko, sizohlola iphesenti lama-ginsenosides ku-ginseng, ukubaluleka kwawo, kanye nemithelela yekhwalithi nokusebenza ngempumelelo kwemikhiqizo ye-ginseng.

Ama-Ginsenosides: Ama-Active Compounds e-Ginseng

I-Ginsenosides ikilasi lezinhlanganisela zemvelo ezitholakala ezimpandeni zesitshalo se-Panax ginseng, kanye nakwezinye izinhlobo ezihlobene zohlobo lwe-Panax. Lezi zinhlanganisela ze-bioactive zihlukile ku-ginseng futhi zinesibopho semiphumela yayo eminingi yemithi. Ama-ginsenosides angama-triterpene saponins, abonakala ngezakhiwo zawo ezihlukahlukene zamakhemikhali nemisebenzi yebhayoloji.

Iphesenti le-ginsenosides ku-ginseng lingahluka kuye ngezinto ezifana nezinhlobo ze-ginseng, ubudala besitshalo, izimo ezikhulayo, kanye nendlela yokukhipha. Ngokuvamile, ingqikithi ye-ginsenoside yokuqukethwe isetshenziswa njengesilinganiso sekhwalithi namandla emikhiqizo ye-ginseng, njengoba ibonisa ukugxila kwezinhlanganisela ezisebenzayo ezibhekene nemiphumela yayo yokwelapha.

Iphesenti lama-Ginsenosides e-Ginseng

Iphesenti le-ginsenosides ku-ginseng lingasuka ku-2% liye ku-6% empandeni, ngokuhlukahluka kuye ngokuthi uhlobo oluthile kanye nengxenye yesitshalo esisetshenziswayo. Isibonelo, i-ginseng ebomvu yaseKorea, elungiswa ngokushisisa nokomisa impande ye-ginseng, ngokuvamile iqukethe amaphesenti aphezulu ama-ginsenosides uma kuqhathaniswa ne-ginseng eluhlaza. Ukwengeza, ukugcwala kwama-ginsenosides angawodwana phakathi kwengqikithi yokuqukethwe kwe-ginsenoside nakho kungahluka, kanti amanye ama-ginsenosides amaningi kakhulu kunamanye.

Iphesenti le-ginsenosides livame ukusetshenziswa njengomaka wekhwalithi namandla emikhiqizo ye-ginseng. Amaphesenti aphezulu we-ginsenosides ngokuvamile ahlotshaniswa namandla amakhulu okwelapha, njengoba lezi zinhlanganisela kukholakala ukuthi zinesibopho semiphumela ye-pharmacological ye-ginseng, okuhlanganisa izakhiwo zayo ze-adaptogenic, anti-inflammatory, kanye ne-immune-modulating.

Ukubaluleka Kokuqukethwe kwe-Ginsenoside

Iphesenti le-ginsenosides ku-ginseng libalulekile ngezizathu eziningana. Okokuqala, isebenza njengesilinganiso sekhwalithi nobuqiniso bemikhiqizo ye-ginseng. Amaphesenti aphezulu ama-ginsenosides akhombisa ukugcwala okuphezulu kwezinhlanganisela ezisebenzayo, okufiselekayo ukuze kuzuzwe imiphumela yokwelapha oyifunayo. Ngakho-ke, abathengi nabakhiqizi bavame ukubheka imikhiqizo ye-ginseng enokuqukethwe okuphezulu kwe-ginsenoside ukuze kuqinisekiswe ukusebenza kwayo.

Okwesibili, iphesenti lama-ginsenosides lingathonya i-bioavailability kanye ne-pharmacokinetics yemikhiqizo ye-ginseng. Ukugxila okuphezulu kwama-ginsenosides kungase kuholele ekumunceni nasekusabalaleni okukhulu kwalezi zinhlanganisela emzimbeni, okungase kuthuthukise imiphumela yazo yokwelapha. Lokhu kubaluleke kakhulu ezithasiselweni ze-ginseng namalungiselelo emithi, lapho i-bioavailability ye-ginsenosides ingaba nomthelela ekusebenzeni kwayo komtholampilo.

Imithelela Yokulawulwa Kwekhwalithi Nokumiswa

Amaphesenti ama-ginsenosides ku-ginseng anemithelela yokulawulwa kwekhwalithi kanye nokumiswa kwemikhiqizo ye-ginseng. Ukulinganisa okukhishwe kwe-ginseng okusekelwe kokuqukethwe kwe-ginsenoside kuvumela ukungaguquguquki ekubunjweni nasekusebenzeni kwamalungiselelo e-ginseng, ukuqinisekisa ukuthi abathengi bathola umkhiqizo onokwethenjelwa nophumelelayo.

Izinyathelo zokulawula ikhwalithi, njenge-high-performance liquid chromatography (HPLC) kanye ne-mass spectrometry, zivame ukusetshenziselwa ukulinganisa okuqukethwe kwe-ginsenoside emikhiqizweni ye-ginseng. Lezi zindlela zokuhlaziya zivumela ukunqunywa okunembile kwephesenti le-ginsenosides, kanye nokuhlonza nokulinganisa ama-ginsenosides ngamanye akhona ekukhishweni.

Ngaphezu kwalokho, iziphathimandla ezilawulayo nezinhlangano zezimboni zingase zisungule imihlahlandlela kanye nemininingwane yokuqukethwe kwe-ginsenoside yemikhiqizo ye-ginseng ukuze kuqinisekiswe ikhwalithi nokuphepha kwayo. Lawa mazinga asiza ukuvikela abathengi emikhiqizweni ye-ginseng eyonakele noma engekho ezingeni futhi akhuthaze ukubonakala kanye nokuziphendulela ngaphakathi kwemboni ye-ginseng.

Isiphetho
Sengiphetha, iphesenti lama-ginsenosides ku-ginseng liyisihluthulelo esiyinhloko sekhwalithi yayo, amandla, kanye nempumelelo yokwelapha. Amaphesenti aphezulu ama-ginsenosides ngokuvamile ahlotshaniswa nemiphumela emikhulu yezokwelapha, okuwenza afiseleke kubathengi abafuna izinzuzo zezempilo ze-ginseng. Ukulinganisa imikhiqizo ye-ginseng ngokusekelwe kokuqukethwe kwe-ginsenoside nokusebenzisa izinyathelo zokulawula ikhwalithi kubalulekile ukuze kuqinisekiswe ukuvumelana nokuthembeka kwamalungiselelo e-ginseng. Njengoba ucwaningo luqhubeka nokuthola amandla okwelapha e-ginsenosides, iphesenti lalezi zinhlanganisela ze-bioactive ku-ginseng lizohlala liyingxenye ebalulekile ekuhlolweni nasekusetshenzisweni kwaleli khambi lekhambi elibalulekile.

Izithenjwa
Attele, AS, Wu, JA, & Yuan, CS (1999). I-Ginseng pharmacology: izakhi eziningi kanye nezenzo eziningi. I-Biochemical Pharmacology, 58(11), 1685-1693.
U-Baeg, IH, & So, SH (2013). Imakethe ye-ginseng yomhlaba kanye ne-ginseng (Korea). Ijenali ye-Ginseng Research, 37(1), 1-7.
Christensen, LP (2009). I-Ginsenosides: amakhemikhali, i-biosynthesis, ukuhlaziya, kanye nemiphumela yezempilo engaba khona. Intuthuko Ocwaningweni Lokudla Nokudla Okunempilo, 55, 1-99.
Kim, JH (2012). I-Pharmacological and medical applications ye-Panax ginseng ne-ginsenosides: ukubuyekezwa okusetshenziselwa izifo zenhliziyo. Ijenali ye-Ginseng Research, 36(1), 16-26.
Vuksan, V., Sievenpiper, JL, & Koo, VY (2008). I-ginseng yaseMelika (i-Panax quinquefolius L) yehlisa i-postprandial glycemia kubantu abangenasifo sikashukela kanye nezifundo ezinesifo sikashukela sohlobo 2. Izingobo zomlando Zomuthi Wangaphakathi, 168(19), 2044-2046.


Isikhathi sokuthumela: Apr-17-2024
fyujr fyujr x