Izindaba - Ingabe Izinsana Zingadla I-Nervonic Acid?

I. Isingeniso

Abazali abaningi bayazibuza ukuthi izinsana zingayidla yini i-nervonic acid. Ngaphambi kokuphendula lo mbuzo, kubalulekile ukuqonda imithombo ye-nervonic acid. Njengoba ubisi lwebele luqukethe i-nervonic acid, umuntu angabuza ukuthi ubisi lwebele alufanele yini ukudliwa. Kodwa ngale kobisi lwebele, ingabe izinsana ezingaphansi kweminyaka emi-3 ubudala zingayidla i-nervonic acid evela kweminye imithombo?

II. Kuyini i-Nervonic Acid?

I-asidi ye-nervonic, eyaziwa nangokuthi i-selacholeic acid, ibizwa ngokwesayensi ngokuthi i-cis-15-tetracosenoic acid. Luhlobo lwe-omega-9 monounsaturated fatty acid. Njengoba itholakale okokuqala ezicutshini zemizwa yezilwane ezincelisayo, ivame ukubizwa ngokuthi i-nervonic acid.

I-Nervonic acid iyingxenye yolwelwesi lwezinto eziphilayo, etholakala kakhulu ngesimo sama-glycolipid nama-sphingomyelin endabeni emhlophe yobuchopho bomuntu, i-retina, isidoda, kanye nezicubu zezinzwa.

III. Izinzuzo ze-Nervonic Acid

Igama elithi "nervonic acid" lisikisela umsebenzi wayo oyinhloko: ukusiza isimiso sezinzwa. Ngaphezu kwalokho, ngenxa yemvelo yayo engagcwele, inikeza nezinzuzo zenhliziyo nemithambo yegazi. Ake sihlolisise ngokujulile:

Kukhuthaza Ukuthuthukiswa Kobuchopho

Ukuqhathaniswa kwezinsana ezizalwa ngaphambi kwesikhathi kanye nezizalwa ngokugcwele kuye kwembula amazinga aphezulu e-nervonic acid ebuchosheni bezingane ezizalwa ngokugcwele. Ucwaningo lubonisa ukuthi i-nervonic acid ingase ithinte ukukhula kokujikeleza kwekhanda lengane.
I-Nervonic acid ilawula ukusebenza kwe-membrane yamaseli obuchopho, ithuthukisa ukudluliselwa kolwazi phakathi kwamangqamuzana obuchopho futhi ikhulisa umsebenzi we-calcium ion. Izifundo zezilwane ziyakusekela lokhu, zibonisa ukuthi izithasiselo ze-nervonic acid zomlomo zingathuthukisa ukufunda kanye nenkumbulo kokubili emagundwini ajwayelekile kanye nalawo akhubazeke inkumbulo ngokuhlola. Ngakho-ke, kucatshangwa ukuthi i-nervonic acid ingathuthukisa inkumbulo yomuntu kanye nokuqonda.

Kuthuthukisa Ukugxila

Isifo Sokuntuleka Kokunaka Okungapheli (ADHD) sibonakala ngokunganaki, ukushesha, kanye nokusebenza ngokweqile. I-ADHD ingaholela ekungaphumelelini kwezemfundo, ubudlelwano obubi bontanga, kanye nokusebenza kabi komphakathi. Izifundo zibonise ukuthi izingane ezine-ADHD zinamazinga aphansi e-nervonic acid egazini lazo uma kuqhathaniswa nezingane ezivamile. Ucwaningo luphakamisa ukuthi ukwengeza inani elanele le-nervonic acid kungathuthukisa izimpawu ze-ADHD kanye nokugxila ezinganeni.

Kunciphisa Ingozi Yokugula Ngengqondo, Isifo Sokucindezeleka kanye Ne-Alzheimer's

Ukuhlaziywa kwabantu asebekhulile abangu-260 abanokukhubazeka kwengqondo kanye namaphrofayili abo e-serum fatty acid kwembule ukwehla kwengozi yesifo i-Alzheimer's (AD) ngamazinga aphezulu e-nervonic acid kanye ne-DHA. Ngaphezu kwalokho, ukuhlolwa kubonise ukuthi uwoyela wembewu yama-maple oqukethe i-nervonic acid ungasebenza ngendlela yokubonisana ye-BDNF/TrkB, wandise ukubonakaliswa kwamaprotheni e-postsynaptic PSD95, GluA1, kanye ne-NMDAR1, futhi wehlise amazinga e-mRNA ezicini zokuvuvukala i-IL-1β, TNFα, kanye ne-IL-6, ngaleyo ndlela kuncishiswe ubuthakathaka bezinzwa futhi kuthuthukiswe inkumbulo kubantu asebekhulile.
Ezinye izifundo zixhumanise amazinga aphansi e-nervonic acid nezimpawu ze-prodromal ze-psychosis kanye nokucindezeleka. Ucwaningo lusikisela ukuthi ukungezelelwa okwanele kwe-nervonic acid kunganciphisa ingozi ye-Alzheimer's, i-psychosis, kanye nokucindezeleka.

Ikhuthaza Ukulungiswa Kwe-Myelin

Ukuhlolwa kwamagundane ane-demyelination ephakelwa uwoyela wembewu ye-maple equkethe i-nervonic acid kubonise ukuthi la magundane acishe alulama ezingeni leqembu lokulawula. Ezinye izifundo zibonise ukuthi ukungezelelwa kokudla nge-nervonic acid kungathuthukisa ukuvuthwa kanye nokubuyiselwa kwe-myelination kwama-oligodendrocyte.

Kunciphisa Ingozi Yesifo Senhliziyo

Izifundo zithole ukuthi i-nervonic acid inganciphisa ingozi yesifo sohlangothi esibi kakhulu. Izizathu zifaka:
Ukulungisa nokuhlanza izindlela ze-neural ezonakele ebuchosheni
Ukubuyisela umsebenzi weziphetho zemizwa
Ukukhuthaza ukuvuselelwa kwamangqamuzana ezinzwa
Ukuvimbela ukuguga kwemizwa yobuchopho
Ukulungisa nokubuyisela izindonga zokuguga, ezonakele, neziqinile zesimiso senhliziyo nemithambo yegazi
Ukuvuselela izicubu zodonga lwemithambo yegazi
Ukubuyisela ukuqina kanye namandla emithambo yegazi

IV. Ingabe Izinsana Zingadla I-Nervonic Acid? Kufanele Ziqale Nini Ukwengeza Imithi?

Impendulo empeleni ilula impela. Ake sihlole ukuhlolwa kweminyango yasekhaya neyamazwe ngamazwe enegunya, kanye nemithethonqubo yokudla efanele.

1. Imithethonqubo ye-FDA

Ngokusho kwemibhalo esemthethweni ye-FDA, i-nervonic acid etholakala kumakhemikhali ingasetshenziswa njengomuthi.
Ukwelapha izifo ezifana ne-isovaleric acidemia, umthamo ungama-200-300mg.

Kodwa-ke, i-FDA ayizange iqinisekise i-nervonic acid evela kweminye imithombo ukuthi isetshenziswe kufomula yezingane. Ngokwemithetho ye-FDA, uma isithako sizosetshenziswa kufomula yezingane, kumele siqashelwe njenge-Generally Recognited as Safe (GRAS) yi-US FDA yefomula yezingane. Ngokusobala i-Nervonic acid ayihlangabezani nale mfuneko.

2. Imithethonqubo ye-EU

I-EU ayizange ibukeze ngokuqondile i-nervonic acid, ngakho-ke akukho lwazi olufanele olutholakalayo.

3. Imithethonqubo yaseShayina

Kusukela mhla zingama-22 kuNdasa 2011, uMnyango Wezempilo wakhipha isaziso esimemezela ukuthi uwoyela wembewu yama-maple wawudlulile isimemezelo esisha sokudla kwemithombo.

Uma kuhlanganiswa imithethonqubo kanye nokubuza okuqukethwe yi-nervonic acid kawoyela wembewu ye-maple, kutholakale ukuthi uwoyela wembewu ye-maple ngokuvamile uqukethe i-nervonic acid engu-3%-5%. Ngokwemithethonqubo yokudla entsha, umkhawulo wokudla kwansuku zonke we-nervonic acid cishe u-150mg.
Njengoba kushiwo ngaphambili, igama lamakhemikhali le-nervonic acid yi-cis-15-tetracosenoic acid. Ngo-2017, i-National Health and Family Planning Commission yakhipha esinye isimemezelo esisha sokudla kwemithombo mayelana namakhemikhali e-nervonic acid atholakala ku-oyili we-rapeseed.

Lesi simemezelo sigcizelele ngqo ukuthi izinsana akufanele zisebenzise imikhiqizo enjalo, futhi uma umkhiqizo usebenzisa ngqo le nhlanganisela, ilebula kufanele ibonise ukuthi ayifanele izinsana.

Ngokusekelwe emithethweni yamanje, kungakhathaliseki ukuthi i-nervonic acid itholakala kumakhemikhali noma emithonjeni yokudla, ayifanele izinsana. Abantu abaningi bangase babuze, "Kodwa uma ubisi lwebele luqukethe, kungani singalusebenzisi?" Lokhu kuhilela izici ezimbili. Okokuqala, okwamanje kunocwaningo olulinganiselwe mayelana nokuphepha kwe-nervonic acid ezinsaneni, futhi ayikasetshenziswa kabanzi emhlabeni jikelele. Ucwaningo olwengeziwe luyadingeka. Okwesibili, ukuthi izinsana zidinga yini ukwengeza i-nervonic acid nakho kungumbuzo ongenalo ucwaningo olwanele. Okwamanje akukho datha eningi yokufakazela ukuthi izinsana azinawo u-nervonic acid. Ngakho-ke, ucwaningo olwengeziwe luyadingeka ukuqinisekisa lokhu.

Ngakho-ke, ngokusekelwe emithethweni kanye nokuhlolwa kwamanje, kunconywa ukuqala ukwengeza i-nervonic acid eneminyaka engu-3 noma ngaphezulu. Abazali abaningi bangase bazizwe bekhululekile uma benezela izingane ezingaphansi kweminyaka engu-3. Ezimweni ezinjalo, kunconywa ukwengeza ukudla.

Ukuze ngiphinde ngiphinde, abukho ubufakazi obanele bokusekela ukwengezwa kwe-nervonic acid ezinganeni. Ngokombono wezokwelapha nowokudla okunempilo, akukho datha ephakamisa ukuthi ukwengezwa kuyadingeka. Ngakho-ke, kunconywa ukuthatha indlela enengqondo yokwengeza i-nervonic acid ezinganeni.

Nakuba wonke umzali enethemba lokuthola umntwana ohlakaniphile, kunconywa ukuthi ugxile ekudleni okunempilo ngenkathi uchitha isikhathi esiningi nomntwana wakho, uhlinzeka ngendawo yokuhlala enempilo, futhi ukhuthaze imisebenzi yangaphandle. Lezi zici zivame ukuba zibaluleke kakhulu.