Izindaba - Ingabe i-Allicin Inenzuzo Ngempilo Yenhliziyo?

I. Isingeniso

Iqhaza lokudla okunomsoco ekugcineni impilo enhle ayinakunakwa. Enye inhlanganisela enamandla ethole ukunakwa ngezinzuzo zayo ezingaba khona zenhliziyo yi-i-allicin. Kulesi sihloko, sibheka izici nezinzuzo ze-allicin empilweni yenhliziyo. I-Allicin iyinhlanganisela ye-bioactive etholakala kugalikhi, eyaziwa ngephunga layo elihlukile nokunambitha. Yakha lapho u-garlic uchotshozwa noma uqotshiwe, ukhulula inhlanganisela yesulfure ebizwa ngokuthi i-alliinase eyenza ukuguqulwa kwe-alliin ibe yi-allicin. Impilo yenhliziyo ibalulekile enhlalakahleni yonke, njengoba inhliziyo iwumgogodla wokumpompa igazi nezakhamzimba kuwo wonke umzimba. Ukugcina inhliziyo enempilo kunganciphisa ingcuphe yezifo zenhliziyo nemithambo yegazi njengokuhlaselwa yinhliziyo nokushaywa unhlangothi, kukwenze kubaluleke ukuhlola amakhambi emvelo angaba khona njenge-allicin.

II. Iyini i-Allicin?

Incazelo Nemithombo

I-Allicin iyinhlanganisela enesibabule ebonisa izakhiwo ezinamandla zokulwa namagciwane kanye ne-antioxidant. Ngaphandle kukagalikhi, i-allicin ingatholakala nakwamanye amalungu omndeni we-Allium, okuhlanganisa u-anyanisi, ama-leeks, nama-shallots.

Izinzuzo Zezempilo ze-Allicin

Izinzuzo zezempilo ze-allicin zidlulela ngale kwezindawo zayo zokulwa namagciwane ezibhalwe kahle. Le nhlanganisela ephawulekayo ibe yindaba yocwaningo olunzulu, eveza izinzuzo eziningi zomzimba ezingathuthukisa kakhulu impilo yonke. Enye yezimfanelo eziphoqelela kakhulu ze-allicin amandla ayo okulwa ne-antioxidant anamandla. Ama-Antioxidants abalulekile ekunciphiseni ama-radicals mahhala-ama-molecule angazinzile angabangela ukucindezeleka okwenziwe nge-oxidative, okuholela ekulimaleni kwamangqamuzana futhi abe nomthelela ekwakhiweni kwezifo ezingapheli. Ngokukhipha lezi zinto eziyingozi, i-allicin isiza ukuvikela umzimba ekulimaleni kwe-oxidative, ngaleyo ndlela ikhuthaze ubuqotho beselula nokuphila isikhathi eside.

Ngaphezu kokuqina kwayo kwe-antioxidant, i-allicin ibonisa imiphumela ephawulekayo yokulwa nokuvuvukala. Ukuvuvukala okungapheli kuya ngokuya kuqashelwa njengesandulela sezindaba ezahlukahlukene zezempilo, okuhlanganisa nesifo senhliziyo, isifo sikashukela, kanye nomdlavuza othile. Ikhono lika-Allicin lokushintsha izindlela zokuvuvukala kungasiza ukunciphisa le ngozi. Ngokuvimbela ukukhiqizwa kwama-cytokines ane-pro-inflammatory nama-enzyme, i-allicin inganciphisa ukuvuvukala kuwo wonke umzimba, ikhuthaze indawo enempilo yangaphakathi.

Ngaphezu kwalokho, i-allicin ikhonjiswe ukuthi inezakhiwo zokwehlisa i-lipid, ezizuzisa kakhulu impilo yenhliziyo. Amazinga aphakeme we-low-density lipoprotein (LDL) cholesterol kanye ne-triglycerides yizici ezibalulekile ezibeka engcupheni yesifo senhliziyo. Ucwaningo lubonisa ukuthi i-allicin ingasiza ekwehliseni amazinga e-cholesterol esewonke futhi ithuthukise isilinganiso se-HDL (high-density lipoprotein) ne-LDL cholesterol. Lo mphumela wokuguqula i-lipid ubalulekile ekugcineni isimiso senhliziyo esinempilo futhi sinciphise ingozi ye-atherosclerosis, isimo esibonakala ngokunqwabelana kwamafutha emithanjeni.

Imvelo ye-Allicin enezici eziningi idlulela endimeni yayo engaba khona ekulawuleni umfutho wegazi. Umfutho wegazi ophakeme, noma umfutho wegazi ophakeme, uyingozi enkulu yesifo senhliziyo nesifo sohlangothi. Ucwaningo luye lwabonisa ukuthi i-allicin ingabangela i-vasodilation, inqubo lapho imithambo yegazi ikhululeka futhi yande, ngaleyo ndlela ithuthukise ukugeleza kwegazi futhi yehlise umfutho wegazi. Lo mphumela unenzuzo ikakhulukazi kubantu abane-hypertension, njengoba kungaholela ekuthuthukisweni okuphawulekayo empilweni yenhliziyo nemithambo yegazi.

Ngaphezu kwalokho, i-allicin ingabamba iqhaza kumetabolism ye-glucose, iyenze ibe umlingani obalulekile kubantu abanesifo sikashukela noma labo abasengozini yokuthola lesi simo. Ucwaningo luphakamisa ukuthi i-allicin ingathuthukisa ukuzwela kwe-insulin futhi ithuthukise ukulawulwa kwe-glycemic, ngaleyo ndlela isize ekulawulweni kwamazinga kashukela egazini. Lokhu kubaluleke kakhulu, njengoba ushukela wegazi ongalawulwa ungaholela ezinkingeni eziningi, kuhlanganise nezinkinga zenhliziyo.

Imiphumela enqwabelene ye-allicin ekucindezelekeni kwe-oxidative, ukuvuvukala, amaphrofayili e-lipid, umfutho wegazi, kanye ne-glucose metabolism igcizelela amandla ayo njengendlela ephelele yezempilo. Njengenhlanganisela yemvelo enomlando ocebile wokusetshenziswa emithini yendabuko, i-allicin inikeza inketho ephoqelelayo kulabo abafuna ukuthuthukisa impilo yenhliziyo yabo kanye nempilo yonke. Ukufakwa kwayo ekudleni okunomsoco, okuhambisana nokunye ukukhetha kwendlela yokuphila enempilo, kungase kunikeze umphumela wokusebenzisana okhuthaza ukuphila isikhathi eside namandla.

III. I-Allicin kanye Nempilo Yenhliziyo

Indlela Yokwenza

Izindlela i-allicin ezithinta ngayo impilo yenhliziyo ziyinkimbinkimbi futhi zihlukahlukene. I-Allicin ikhuthaza i-vasodilation, yandisa imithambo yegazi ukuthuthukisa ukugeleza kwegazi nokunciphisa umfutho wegazi. Lo mphumela ulamula ngokuyinhloko ngokukhululwa kwe-nitric oxide, ekhulula amangqamuzana emisipha abushelelezi ezindongeni zemithambo yegazi. Ngokuthuthukisa ukugeleza kwegazi, i-allicin ayigcini nje ngokukwehlisa umfutho wegazi kodwa futhi iqinisekisa ukuthi izitho ezibalulekile zithola umoya-mpilo owanele nezakhamzimba.
Ukwengeza, i-allicin ingase ivimbele ukuhlangana kweplatelet, okubalulekile ekuvimbeleni i-thrombosis—isici esiyingozi esiyingozi sokuhlaselwa yinhliziyo nokushaywa unhlangothi. Ngokuphazamisa ukusebenza kweplatelet, i-allicin isiza ukugcina ukugeleza kwegazi okushelelayo, inciphisa ingozi yokwakheka kwamahlule. Impahla yayo ye-antithrombotic inenzuzo ikakhulukazi kulabo abasengozini yezenzakalo zenhliziyo nemithambo yegazi.
Ngaphezu kwalokho, izakhiwo ze-allicin ze-antioxidant zidlala indima ebalulekile ekulweni nengcindezi ye-oxidative, enomthelela ezifweni zenhliziyo. I-Allicin isusa ama-radicals mahhala, ivikela amangqamuzana e-endothelial-amangqamuzana ahlanganisa imithambo yegazi-ekulimaleni kwe-oxidative. Lo mphumela wokuvikela ubalulekile ekugcineni umsebenzi we-endothelial, obalulekile empilweni yenhliziyo nemithambo yegazi.

Ucwaningo kanye nemiphumela yocwaningo

Ucwaningo oluningi luye lwagqamisa izinzuzo zenhliziyo nemithambo ye-allicin, ezisekela ukufakwa kwayo kumasu empilo yenhliziyo. Isibonelo, ukuhlaziywa kwe-meta kwembula ukuthi ukufakwa kukagalikhi, okucebile ku-allicin, kunciphisa kakhulu umfutho wegazi ezigulini ezinomfutho wegazi ophakeme. Ukulawula umfutho wegazi kuyisihluthulelo sokuvimbela izifo zenhliziyo.
Olunye ucwaningo lwabonisa ikhono le-allicin lokwehlisa i-cholesterol namazinga e-triglyceride, okunciphisa ingozi ye-atherosclerosis. I-cholesterol ephakeme iyisici esiyingozi esaziwayo sokwakheka kwama-plaque emithanjeni, okuholela ezinkingeni zenhliziyo. Ngokuthuthukisa amaphrofayili e-lipid, i-allicin ifaka isandla ohlelweni olunempilo lwenhliziyo nemithambo yegazi.
Ngaphezu kwalokho, ucwaningo lubonisa ukuthi i-allicin ingathuthukisa umsebenzi we-endothelial. Ukukhishwa kukagalikhi kwatholakala kuthuthukisa i-vasodilation encike endothelial, okuphakamisa ukuthi i-allicin ingabuyisela ukusebenza okujwayelekile kwemithambo kulabo abanempilo yenhliziyo esengozini. Lokhu okutholakele kugcizelela indima ethembisayo ye-allicin empilweni yenhliziyo.

Izinzuzo Ezingaba Khona Zempilo Yenhliziyo

I-Allicin inikeza izinzuzo eziningi zempilo yenhliziyo, okuhlanganisa amaphrofayili e-lipid athuthukisiwe, ukwehla komfutho wegazi, nokusebenza kwe-endothelial okuthuthukisiwe. Ikhono layo lokwehlisa i-cholesterol ye-LDL kanye ne-triglycerides ngenkathi ikhulisa i-cholesterol ye-HDL inciphisa ingozi ye-atherosclerosis nemicimbi yenhliziyo.
Izakhiwo zika-Allicin zokuqeda ukuvuvukala zingasiza futhi ekwehliseni ukuvuvukala okungapheli, okunomthelela owaziwayo ezifweni zenhliziyo. Ngokwehlisa izimpawu zokuvuvukala emzimbeni, i-allicin inganciphisa ubungozi bezimo ezifana nesifo se-coronary artery kanye nokuhluleka kwenhliziyo.
Sengiphetha, imiphumela ehlukahlukene ye-allicin kumfutho wegazi, amaphrofayili e-lipid, umsebenzi we-endothelial, nokuvuvukala kwenza kube inketho ephoqelelayo yokuthuthukisa inhlalakahle yenhliziyo. Njengoba ucwaningo luqhubeka, i-allicin ingaba isisekelo kumasu okudla okuhloswe ngawo ukukhuthaza impilo yenhliziyo.

IV. Izingozi kanye nemiphumela emibi ye-Allicin

Ukusebenzisana Okungenzeka Nemithi

Nakuba i-allicin ngokuvamile ibhekwa njengephephile uma idliwe isesimweni sokudla, ukuqapha kuyafaneleka uma kuziwa ezithakweni noma ezinhlotsheni ezigxilile ze-allicin. Lawa malungiselelo agxilile angasebenzisana nemithi ehlukahlukene, ikakhulukazi ama-anticoagulant noma izinto ezinciphisa igazi njenge-warfarin ne-aspirin. I-Allicin inamandla okuthuthukisa imiphumela yale mithi, okwandisa ingozi yokopha. Lokhu kusebenzisana kuthinta ikakhulukazi abantu abahlinzwayo noma labo abanezinkinga zokopha.
Ukwengeza, i-allicin ingase ithinte umzimba wezidakamizwa ezithile ezicutshungulwa yisibindi. Kungaba nomthelela ekusebenzeni kwama-enzyme e-cytochrome P450, adlala indima ebalulekile kumetabolism yezidakamizwa. Lokhu kuguqulwa kungaholela ekwenyukeni kobuthi noma ukuncipha kokusebenza kwemithi, kuye ngomuthi othile ohilelekile. Ngakho-ke, kuyancomeka ukuthi uxhumane nomhlinzeki wezempilo ngaphambi kokufaka izithasiselo ze-allicin ohlelweni lwakho lokwelapha, ikakhulukazi uma uthatha imithi kadokotela noma unezimo zempilo ezicashile.

Imiphumela Emibi Yokusebenzisa I-Allicin

Kwabanye abantu, imithamo ephezulu ye-allicin ingase iholele ezindabeni zesisu, okuhlanganisa isilungulela, ukuqunjelwa, noma ukungagayeki kahle kokudla. Le miphumela emibi ingavezwa ikakhulukazi kulabo abazwela ugarliki noma ama-compounds anesulfure. Nakuba ukusetshenziswa okusesilinganisweni kokudla okunothe nge-allicin ngokuvamile kubekezelelwa kahle, ukudla ngokweqile—ikakhulukazi kufomu lokwengeza—kungenza lezi zimpawu zibe zimbi nakakhulu.
Ngaphezu kwalokho, iphunga elinamandla elihlotshaniswa ne-allicin lingase libangele abanye, okuholela ekungaphatheki kahle emphakathini noma ekuphoxekeni. Leli phunga liwumkhiqizo wemvelo we-allicin futhi lingahlala phezu kokuphefumula nasesikhumbeni, okungase kuvimbele abantu ukuthi badle ugaliki noma ukudla okunothe nge-allicin njalo.
Kubalulekile ukubhekana nokusetshenziswa kwe-allicin ngokulinganisela nangokuqaphela amazinga okubekezelela komuntu ngamunye. Ukuqala ngamanani amancane futhi kancane kancane ukwandisa ukudla kungasiza ekwehliseni imiphumela engemihle engaba khona. Kulabo ababhekana nokusabela okungekuhle, kungase kube usizo ukubonana nochwepheshe bezempilo ukuze nixoxe ngeminye imithombo ye-allicin noma ezinye izinguquko zokudla.
Kafushane, ngenkathi i-allicin inikeza izinzuzo eziningi zezempilo, kubalulekile ukuqaphela ukusebenzisana kwayo okungaba khona nemithi kanye nokuba khona kwemiphumela engemihle. Ngokusebenzisa ukuqapha nangokufuna isiqondiso sochwepheshe, abantu bangafaka i-allicin ngokuphephile ekudleni kwabo futhi bajabulele izinzuzo zayo zenhliziyo nemithambo yegazi ngaphandle kwengozi engadingekile.

V. Indlela Yokuhlanganisa I-Allicin ekudleni

Ukudla Okuphezulu ku-Allicin

Ukuze usebenzise izinzuzo ze-allicin, faka u-garlic, u-anyanisi, ama-leeks, nama-shallots ekudleni kwakho kwansuku zonke. Lokhu kudla akuhlinzeki nge-allicin kuphela kodwa futhi nohlu lwezinye izinhlanganisela ezizuzisayo ezisekela impilo yenhliziyo kanye nempilo yonke.

Amathiphu Okupheka Nokulungiselela

Ukwandisa okuqukethwe kwe-allicin ku-garlic, yichoboze noma uyinqume futhi uyivumele ukuthi ihlale imizuzu embalwa ngaphambi kokupheka. Ukupheka u-garlic emazingeni okushisa aphansi isikhathi esifushane kungasiza ekulondolozeni i-allicin eningi, kuqinisekiswe ukuthi uthola okuningi kule nhlanganisela enenzuzo.

Isiphetho

Sengiphetha, i-allicin ibonisa isithembiso njengesithako semvelo esinezinzuzo ezingaba khona zezempilo yenhliziyo. Ngokufaka ukudla okunothe nge-allicin ekudleni kwakho nokulandela izincomo ezisekelwe ebufakazini, ungakwazi ukusekela inhlalakahle yakho yenhliziyo nokunciphisa ingozi yezinkinga ezihlobene nenhliziyo.
Ucwaningo olwengeziwe mayelana nezinqubo ezithile ze-allicin empilweni yenhliziyo, imithamo elungile, kanye nemiphumela yesikhathi eside kuyafaneleka ukuze sijulise ukuqonda kwethu le nhlanganisela ethakazelisayo. Uphenyo oluqhubekayo mayelana nendima ye-allicin ekugcineni impilo yenhliziyo ingase iholele kumasu amasha okuvimbela nokwelapha izifo zenhliziyo nemithambo yegazi.