Izindaba - Isayensi Engemuva Kwe-Organic Agaricus Blazei Extract

I. Isingeniso

I-Agaricus blazei, eyaziwa nangokuthi "i-cogumelo do sol" noma "i-sun mushroom", ithole ukunakwa okukhulu eminyakeni yamuva ngenxa yezinzuzo zayo zezempilo ezingaba khona. Lesi sihloko sihlola ucwaningo lwesayensi ngemuva i-organic Agaricus blazei extractkanye nezakhiwo zayo zokwelapha ezithembisayo.

Yini Eyenza I-Organic Agaricus Blazei Iphumelele Kangaka?

I-Organic Agaricus blazei extract iqukethe inhlanganisela eyingqayizivele yamakhemikhali asebenzayo afaka isandla emandleni ayo okwelapha:

-Ama-Beta-glucan:Lawa ama-polysaccharide ayinkimbinkimbi atholakala ezikhunta nasezitshalweni ezahlukahlukene. Ama-beta-glucan aziwa kakhulu ngekhono lawo lokuguqula isimiso somzimba sokuzivikela. Ezinye izifundo ziphakamisa ukuthi anezakhiwo zokulwa nomdlavuza, okungenzeka zisize ekuvimbeleni noma ekwelapheni umdlavuza ngokukhulisa ikhono lesimiso somzimba sokuzivikela lokuhlasela amangqamuzana anomdlavuza.

-I-Ergosterol:I-Ergosterol iyinhlanganisela ye-sterol etholakala ku-fungi futhi isebenza njengesandulela se-vitamin D2 uma ivezwa ekukhanyeni kwe-ultraviolet. Kuye kwabonakala ukuthi ikhombisa izakhiwo zokulwa nokuvuvukala kanye ne-antioxidant, ezingasiza ekuvikeleni umzimba ekucindezelekeni kwe-oxidative kanye nokuvuvukala.

-UBlazein:I-Blazein iyinhlanganisela ye-sterol etholakala kwezinye izikhunta, ikakhulukazi amakhowe adliwayo. Ithole ukunakwa ngenxa yezakhiwo zayo ezingaba khona zokulwa nomdlavuza. Ucwaningo lubonisa ukuthi i-blazein ingasiza ekuvimbeleni ukukhula kwamaseli omdlavuza ngokuphazamisa izinqubo zamaseli, yize kudingeka izifundo ezengeziwe ukuze kuqondwe ngokugcwele amandla ayo okwelapha ekuvimbeleni nasekwelapheni umdlavuza.

-I-Agaritine:I-Agaritine iyinhlanganisela yemvelo etholakala kumakhowe, ikakhulukazi ezinhlotsheni ze-Agaricus. Nakuba kuyimpikiswano ngenxa yobuthi obungaba khona uma idliwa ngobuningi, olunye ucwaningo lubonisa ukuthi ingaba nemiphumela yokulwa nomdlavuza.

Ukuxhumana okusebenzisanayo phakathi kwala ma-compounds kukholakala ukuthi kuthuthukisa imiphumela yokwelapha iyonke ye-Agaricus blazei extract. Ukutshalwa kwe-organic kuqinisekisa ukuthi la ma-compounds awusizo akhiqizwa ngaphandle kokuchayeka ezibulala-zinambuzane noma kumanyolo okwenziwa.

Izakhamzimba Ezibalulekile ku-Organic Agaricus Blazei Yezempilo

Ngaphandle kwamakhemikhali ayo ayingqayizivele e-bioactive,i-organic Agaricus blazei extractukudla okuphezulu okugcwele izakhamzimba:

-Amaprotheni:Ihlinzeka ngawo wonke ama-amino acid abalulekile, okwenza kube umthombo ophelele wamaprotheni. Lokhu kuyenza ibe inketho enhle kakhulu yokusekela ukukhula kwemisipha, ukulungiswa, kanye nokusebenza komzimba wonke.

-Ifayibha:Icebile ngefayibha encibilikayo nengancibiliki, ikhuthaza ukugaya ukudla okunempilo. Ifayibha encibilikayo isiza ukulawula amazinga e-cholesterol, kuyilapho ifayibha engancibiliki isiza ekugcineni ukuhamba kwamathumbu njalo.

-Amavithamini:Umthombo omuhle wamavithamini e-B njenge-riboflavin, i-niacin, ne-pantothenic acid, abalulekile ekukhiqizweni kwamandla, ekugayweni kwe-metabolism, nasekugcinweni kwesikhumba nezinzwa ezinempilo.

-Amaminerali:Iqukethe amaminerali abalulekile njenge-potassium, i-phosphorus, i-magnesium, ne-selenium. Lawa maminerali asekela imisebenzi ehlukahlukene yomzimba, okuhlanganisa ukulinganisela koketshezi, impilo yamathambo, kanye nokuvikela ama-antioxidant.

-Ama-Antioxidant:Ukuba khona kwamakhemikhali e-phenolic kanye ne-ergothioneine kunikeza isivikelo esinamandla se-antioxidant, okusiza ekunciphiseni ama-free radicals nokunciphisa ukucindezeleka kwe-oxidative, ngaleyo ndlela kusekela impilo iyonke.

Ukutshalwa kwe-Agaricus blazei ngendlela yemvelo kungabangela ukuminyana kwezakhamzimba okuphezulu uma kuqhathaniswa namakhowe akhuliswa ngendlela evamile, yize kudingeka ucwaningo olwengeziwe ukuqinisekisa lokhu ngokuqinisekile.

Ucwaningo Ngezakhiwo Zokwelapha Zika-Agaricus Blazei

Izifundo zesayensi ziphenye izinzuzo ezahlukahlukene ezingaba khona zezempilo ze-Agaricus blazei extract:

Ukusekelwa Kwesistimu Yokuzivikela Emzimbeni

Izifundo eziningi zibonise imiphumela yokulawula amasosha omzimbai-organic Agaricus blazei extractama-polysaccharides:

- Ukukhiqizwa okwandisiwe kwama-cytokine njenge-interleukin-1 beta kanye ne-tumor necrosis factor-alpha

- Umsebenzi othuthukisiwe wamaseli okubulala wemvelo

- Ukukhuthaza umsebenzi we-macrophage kanye ne-T-lymphocyte

Le miphumela ingase ibe negalelo ekuthuthukiseni ukumelana nezifo futhi ingase isekele izimpendulo zomzimba zokulwa nomdlavuza.

Amandla Okulwa Nomdlavuza

Nakuba izivivinyo zemitholampilo zabantu zilinganiselwe, ucwaningo lwangaphambi kokwelashwa lubonise imiphumela ethembisayo yokulwa nomdlavuza:

- Ukuvinjelwa kokukhula kwesimila ezinhlotsheni zezilwane zezinhlobo ezahlukene zomdlavuza

- Ukuqaliswa kwe-apoptosis (ukufa kwamangqamuzana okuhleliwe) emigqeni yamangqamuzana omdlavuza

- Amandla okuthuthukisa ukusebenza kahle kwe-chemotherapy evamile

Kudingeka izifundo eziqinile zabantu ukuqinisekisa le miphumela nokunquma umthamo kanye nokuphepha okufanele.

Impilo Yomzimba

Ucwaningo oluthile lubonisa ukuthi i-Agaricus blazei extract ingaba nemiphumela emihle kumapharamitha okusebenza kwe-metabolic:

- Ukuzwela kwe-insulin okuthuthukisiwe kanye nokusetshenziswa kwe-glucose kumamodeli ezilwane ezinesifo sikashukela

- Ukwehla kwamazinga e-cholesterol ephelele kanye ne-triglyceride

- Imiphumela engaba khona yokwehlisa isisindo ngokuguqulwa kwe-gut microbiota

Kudingeka izivivinyo zemitholampilo zabantu ukuqinisekisa lokhu okutholakele kokuqala.

Ukuvikelwa Kwesibindi

Izifundo zezilwane zibonise imiphumela yokuvikela isibindii-organic Agaricus blazei extract:

- Ukulimala kwesibindi okuncishisiwe kumamodeli okulimala kwesibindi okubangelwa izidakamizwa

- Imiphumela ye-Antioxidant engavikela amangqamuzana esibindi ekucindezelekeni kwe-oxidative

- Amandla okusekela ukuvuselelwa kwesibindi

Ucwaningo olwengeziwe luyadingeka ukuze kuhlolwe izindlela ezingemuva kwale miphumela kanye nezicelo zayo zezokwelapha ezingaba khona.

Umsebenzi Wokulwa Nokuvuvukala

Izakhiwo zokulwa nokuvuvukala ze-Agaricus blazei zihlolisisiwe ezimweni ezahlukene:

- Ukunciphisa izimpawu zokuvuvukala kumamodeli ezilwane ane-colitis

- Izinzuzo ezingaba khona ezimweni zokungezwani komzimba njenge-asthma

- Ukuguqulwa kwezindlela zokuvuvukala ezihambisana nesifo senhliziyo

Le miphumela yokulwa nokuvuvukala ingase ibe negalelo ezimpahleni ezithuthukisa impilo ze-Agaricus blazei extract.

Isiphetho

Ucwaningo lwesayensi mayelana nesithako se-Agaricus blazei esiphilayo luveza uhlu oluyinkimbinkimbi lwamakhemikhali asebenzayo anamandla okwelapha athembisayo. Nakuba kudingeka izivivinyo ezengeziwe zemitholampilo kubantu ukuze kucaciswe ngokugcwele imiphumela yaso, ubufakazi obutholakalayo busikisela ukuthi lesi sithako samakhowe singase sinikeze ukwesekwa kokusebenza komzimba, impilo ye-metabolic, kanye nokuvimbela umdlavuza okungenzeka.

Njengoba isithakazelo ezixazululweni zemvelo zezempilo siqhubeka nokukhula, i-organic Agaricus blazei extract imelela indawo ethakazelisayo yokuhlola okwengeziwe kwesayensi. Iphrofayili yayo yezakhamzimba eyingqayizivele kanye namakhemikhali ahlukahlukene asebenzayo kuyenza ibe yinto ewusizo emhlabeni wamakhowe ezokwelapha. Ukuze uthole ulwazi olwengeziwe ngekhwalithi ephezului-organic Agaricus blazei extractkanye nezinye izithako zezitshalo, sicela usithinte ku-grace@biowaycn.com.

Izinkomba

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  2. 2. Hetland G, Johnson E, Lyberg T, Kvalheim G. I-Mushroom Agaricus blazei Murill Iveza Imiphumela Yezokwelapha Ku-Tumor, Ukutheleleka, Ukungezwani Nomzimba, Nokuvuvukala Ngokushintsha Kwayo Ukungavikeleki Kwangaphakathi Nokuthuthukisa Ukungalingani Nokuvuvukala Kwe-Th1/Th2. Adv Pharmacol Sci. 2011;2011:157015.
  3. 3.Wu MF, Chen YL, Lee MH, nabanye. Umphumela we-Agaricus blazei Murrill extract kumaseli omdlavuza wamathumbu abantu e-HT-29 kumagundane e-SCID aphilile. Ku-Vivo. 2011;25(4):673-677.
  4. 4. Yamanaka D, Motoi M, Ishibashi K, nabanye. Umphumela we-Agaricus brasiliensis KA21 emsebenzini wokulwa nomdlavuza kanye nezimpendulo zomzimba ezifweni ezithwala umdlavuza. J Nutr Sci Vitaminol (Tokyo). 2013;59(3):234-240.
  5. 5.Kozarski M, Klaus A, Nikšić M, et al. Imisebenzi ye-Antioxidative kanye nokuhlukaniswa kwamakhemikhali kwezingcezu ze-polysaccharide ezivela kumakhowe asetshenziswa kabanzi i-Ganoderma applanatum, i-Ganoderma lucidum, i-Lentinus edodes kanye ne-Trametes versicolor. J Food Compos Anal. 2012;26(1-2):144-153.