Ukuqalisa
GinsenosidesIngabe isigaba sezinto zemvelo ezitholakala ezimpandeni zePanax Ginseng Plant, esetshenziselwe amakhulu eminyaka emithini yendabuko yaseChina. Lezi zinhlanganisela ezi-bioactive zithole ukunakwa okugcwele eminyakeni yamuva ngenxa yezinzuzo zazo zezempilo. Kulesi sihloko, sizohlola izinzuzo ezahlukahlukene ze-ginsenosides, kufaka phakathi imiphumela yazo emsebenzini wokuqonda, ukuguquguquka kwamasosha omzimba, izindlela zokulwa nokuvuvukala, kanye nomsebenzi ongaba khona we-anticancer, kanye nomsebenzi ongaba khona we-anticancer, kanye nomsebenzi ongaba khona we-anticancer, kanye nomsebenzi ongaba khona we-anticancer, kanye nomsebenzi ongaba khona we-anticancer, kanye nomsebenzi ongaba khona we-anticancer, kanye nomsebenzi ongaba khona we-anticancer.
Umsebenzi wokuqonda
Enye yezinzuzo ezaziwa kakhulu ze-ginsenosides amandla abo okuthuthukisa umsebenzi wokuqonda. Izifundo eziningana zikhombisile ukuthi ama-ginsenosides angathuthukisa inkumbulo, ukufunda, nokusebenza kokuqonda okuphelele. Le miphumela kucatshangwa ukuthi ixazululwa ngezinqubo ezahlukahlukene, kufaka phakathi ukuguquguquka kwama-neurotransmitters, njenge-acetylcholine ne-dopamine, kanye ne-neurogenesis, inqubo yokukhiqiza ama-neurons amasha ebuchosheni.
Ocwaningweni olushicilelwe ejeni le-ethnopharmasAmology, abacwaningi bathola ukuthi ama-ginsenosides angathuthukisa ukufundwa kwendawo kanye nememori ngamagundane ngokuthuthukisa ukubonakaliswa kwe-neurotrophic factor (BDNF), amaprotheni asekela ukusinda nokukhula kwama-neurons. Ngokwengeziwe, ama-ginsenosides aboniswe ukuvikela ukwehla okuhlobene nokuqonda okuhlobene nobudala kanye nezifo ze-neurodegenerative, njengezifo ze-Alzheimer's kanye neParkinson, ngokunciphisa ukucindezelwa kwe-oxidative nokuvuvukala ebuchosheni.
Ukushintshashintsha kwamasosha omzimba
Ama-ginsenosides atholakele futhi ahumusha amasosha omzimba, athuthukise amandla awo okuvikela ezifweni nasezifo. Lezi zinhlanganisela zikhonjiswe ukukhuthaza ukukhiqizwa kanye nomsebenzi wamangqamuzana amasosha omzimba afana namaseli wemvelo wokubulala, ama-macrophages, nama-t lymphocyte, adlala indima ebalulekile ekuvikelweni komzimba kanye namangqamuzana omdlavuza.
Ucwaningo olushicilelwe kwi-ImmunophArmarmacology Journal lubonise ukuthi ama-ginsenosides angathuthukisa ukuphendula izivintu egunjini ngokwandisa ukukhiqizwa kwama-cytokines, okusayina ama-molecule alawulwa umsebenzi wokuvikela amakhono. Ngaphezu kwalokho, ama-ginsenosides aboniswe ukuthi anezakhiwo ze-anti-viral ne-anti-bacterial, zibenze bayenzele ikhambi lemvelo elithembisayo lokusekela impilo yezempilo yokuzivikela komzimba nokuvimbela izifo.
Izakhiwo zokulwa nokuvuvukala
Ukuvuvukala kuyimpendulo yemvelo yamasosha omzimba ukulimala nokutheleleka, kepha ukuvuvukala okungapheli kungafaka isandla ekuthuthukisweni kwezifo ezahlukahlukene, kufaka nesifo senhliziyo, isifo sikashukela kanye nomdlavuza. Ama-ginsenosides atholakele ukuthi anezakhiwo ezinamandla zokulwa nokuvuvukala, ezingasiza ekunciphiseni imiphumela elimazayo yokuvuvukala okungapheli emzimbeni.
Ucwaningo olushicilelwe kwiphephabhuku ucwaningo lweGinseng lwabonisa ukuthi ama-ginsenosides angacindezela ukukhiqizwa kwama-cytokines wokuvuvukala okuvuvukala futhi avimbele ukusebenza kwezindlela zokugibela ukuvulela amaseli omzimba. Ngokwengeziwe, ama-ginsenosides aboniswe ukunciphisa ukubonakaliswa kwama-medrator wokuvuvukala, njengeCyclooXygenase-2 (COX-2) kanye ne-Imputible nitric oxide synthase (i-Inos), ebandakanyeka ekuphenduleni kokuvuvukala.
Umsebenzi we-Anticancer
Enye indawo enentshisekelo yocwaningo lwe-ginsenoside ngumsebenzi wabo we-anticancer. Izifundo eziningana ziphakamise ukuthi ama-ginsenosides angahle asebenzise imiphumela yokulwa nomdlavuza ngokuvimbela ukukhula kanye nokwanda kwamaseli umdlavuza, nokucindezela amaseli okufa (ukucindezela imithambo yegazi emisha yokusekela ukukhula kwezikhukhula).
Ukubuyekezwa okushicilelwe ku-International Journal of Molecular Science kugcizelele amandla ama-anticancer ama-ginsenosides, ikakhulukazi esifubeni, amaphaphu, isibindi, nomdlavuza we-collectal. Ukubuyekezwa kuxoxwe ngezindlela ezahlukahlukene lapho ama-ginsenosides asebenzisa khona imiphumela yabo yokulwa nomdlavuza, okubandakanya ukuguquguquka kwezindlela zokugibela amaseli, umthetho wokuthuthuka komjikelezo weseli, kanye nokwenza ngcono ukuphendula komzimba okumelene nomdlavuza wamaseli.
Ukugcina
Ekuphetheni, ama-ginsenosides ayizinhlanganisela ze-bioactive ezitholakala ePanax Ginseng ezinikela ngezinzuzo eziningi ezingaba khona zezempilo. Lokhu kufaka phakathi intuthuko emsebenzini wokuqonda, ukuguqulwa kwamasosha omzimba, izakhiwo zokulwa nokuvuvukala, kanye nomsebenzi ongaba khona we-anticancer. Ngenkathi kudingeka ucwaningo oluthe xaxa ukuze uqonde ngokugcwele izindlela zokwenziwa kanye namathuba okulashwa e-ginsenosides, ubufakazi obukhona bubonisa ukuthi lezi zinhlanganisela zibamba isethembiso njengezinkulumo zemvelo zokukhuthaza impilo yonke nenhlala-kahle.
Ukunqubekela phambili
Kim, JH, & Yi, YS (2013). UGinnsenoside RG1 ucindezela ukusebenza kwamangqamuzana ama-dendritic kanye ne-t cell calroliflotion eVitro naseVivo. Immunompacology yamazwe aphesheya, 17 (3), 355-362.
ILeung, KW, & Wong, njengoba (2010). Pharmacolology of ginsenosides: Ukubuyekezwa kwezincwadi. Imithi yaseChina, 5 (1), 20.
I-Radad, K., Gille, G., uLiu, L., Rausch, WD, kanye nokusetshenziswa kwe-ginseng kwezokwelapha ngokugcizelelwa kwezifo ze-neurodegenerative. Ijenali yeScarmacogical Science, 100 (3), 175-186.
Wang, y., & liu, j. (2010). I-GINSEng, isu elingaba khona le-neuroprotuctive. Umuthi ohambisanayo wobufakazi kanye nomunye umuthi, 2012.
Yun, tk (2001). Ukwethulwa okufushane kwePanax Ginnseng Ca Meyer. I-Journal of Korean Medical Science, 16 (Vala), S3.
Isikhathi sePosi: APR-16-2024
