Yiziphi Izinzuzo ze-Ginsenosides?

Umsebenzi wokuqonda

Enye yezinzuzo ezaziwa kakhulu ze-ginsenosides amandla awo okuthuthukisa ukusebenza kwengqondo. Ucwaningo oluningi luye lwabonisa ukuthi i-ginsenosides ingathuthukisa inkumbulo, ukufunda, nokusebenza kwengqondo okuphelele. Le miphumela kucatshangwa ukuthi iqondiswa ngezindlela ezihlukahlukene, kuhlanganise nokuguqulwa kwama-neurotransmitters, njenge-acetylcholine ne-dopamine, kanye nokukhuthazwa kwe-neurogenesis, inqubo yokukhiqiza ama-neurons amasha ebuchosheni.

Ocwaningweni olwanyatheliswa kuyi-Journal of Ethnopharmacology, abacwaningi bathola ukuthi i-ginsenosides ingathuthukisa ukufunda kwendawo kanye nenkumbulo kumagundane ngokuthuthukisa ukubonakaliswa kwe-brain-derived neurotrophic factor (BDNF), iphrotheni esekela ukusinda nokukhula kwama-neurons. Ukwengeza, ama-ginsenosides akhonjiswe ukuthi avikela ukwehla kwengqondo okuhlobene neminyaka kanye nezifo ze-neurodeergenerative, njenge-Alzheimer's and Parkinson's disease, ngokunciphisa ukucindezeleka okwenziwe nge-oxidative nokuvuvukala ebuchosheni.

Ukuguqulwa Kwesistimu Yamasosha omzimba

I-Ginsenosides nayo itholakale ukuthi ishintsha amasosha omzimba, ithuthukisa amandla ayo okuzivikela ezifweni nasezifweni. Lezi zinhlanganisela ziye zaboniswa ukuze zikhuthaze ukukhiqizwa nokusebenza kwamangqamuzana ahlukahlukene omzimba omzimba, njengamangqamuzana abulalayo emvelo, ama-macrophage, nama-T lymphocyte, adlala indima ebalulekile ekuvikelweni komzimba kumagciwane namangqamuzana omdlavuza.

Ucwaningo olwanyatheliswa kujenali ye-International Immunopharmacology lubonise ukuthi i-ginsenosides ingathuthukisa ukusabela komzimba kumagundane ngokwandisa ukukhiqizwa kwama-cytokines, angama-molecule akhombisayo alawula ukusebenza kwamangqamuzana omzimba omzimba. Ngaphezu kwalokho, i-ginsenosides ikhonjiswe ukuthi inezindawo ezilwa namagciwane kanye ne-anti-bacterial, okuwenza abe ikhambi lemvelo elithembisayo lokusekela impilo yokuzivikela komzimba nokuvikela izifo.

Izakhiwo Zokulwa Nokuvuvukala

Ukuvuvukala kuwukusabela okungokwemvelo kwamasosha omzimba ekulimaleni nasekuthelelekeni, kodwa ukuvuvukala okungapheli kungaba nomthelela ekwakhiweni kwezifo ezihlukahlukene, kuhlanganise nesifo senhliziyo nemithambo yegazi, isifo sikashukela, nomdlavuza. Ama-ginsenosides atholwe anezinto ezinamandla zokulwa nokuvuvukala, ezingasiza ekwehliseni imiphumela eyingozi yokuvuvukala okungapheli emzimbeni.

Ucwaningo olushicilelwe ku-Journal of Ginseng Research lubonise ukuthi i-ginsenosides ingacindezela ukukhiqizwa kwama-cytokines ane-pro-inflammatory futhi ivimbele ukusebenza kwezindlela zokubonisa ukuvuvukala kumaseli omzimba. Ukwengeza, i-ginsenosides iboniswe ukunciphisa ukubonakaliswa kwabaxhumanisi abavuthayo, njenge-cyclooxygenase-2 (COX-2) ne-inducible nitric oxide synthase (iNOS), ehilelekile ekuphenduleni ukuvuvukala.

Umsebenzi Wokulwa Nomdlavuza

Enye indawo enentshisekelo ocwaningweni lwe-ginsenoside umsebenzi wabo ongase ube khona wokulwa nomdlavuza. Ucwaningo oluningana luphakamise ukuthi ama-ginsenosides angase abe nemiphumela elwa nomdlavuza ngokuvimbela ukukhula nokusabalala kwamangqamuzana omdlavuza, enze i-apoptosis (ukufa kweseli okuhleliwe), futhi acindezele isimila angiogenesis (ukwakheka kwemithambo yegazi emisha ukusekela ukukhula kwesimila).

Ukubuyekezwa okushicilelwe kuyi-International Journal of Molecular Sciences kugqamise amandla e-anticancer e-ginsenosides, ikakhulukazi kumdlavuza webele, wamaphaphu, wesibindi kanye nowomdlavuza. Ukubuyekezwa kuxoxisane ngezindlela ezihlukahlukene ama-ginsenosides enza ngazo imiphumela yokulwa nomdlavuza, okuhlanganisa ukuguquguquka kwezindlela zokubonisa amangqamuzana, ukulawulwa kokuqhubeka komjikelezo wamangqamuzana, kanye nokuthuthukiswa kokusabela komzimba ngokumelene namangqamuzana omdlavuza.

Isiphetho

Sengiphetha, ama-ginsenosides ayizinhlanganisela ze-bioactive ezitholakala ku-Panax ginseng ezinikeza inhlobonhlobo yezinzuzo zezempilo ezingaba khona. Lokhu kufaka phakathi ukuthuthukiswa kokusebenza kwengqondo, ukuguquguquka kwamasosha omzimba, izakhiwo zokulwa nokuvuvukala, kanye nomsebenzi ongase ube khona wokulwa nomdlavuza. Nakuba ucwaningo olwengeziwe ludingeka ukuze kuqondwe ngokugcwele izindlela zokwenza kanye namandla okwelapha e-ginsenosides, ubufakazi obukhona bubonisa ukuthi lezi zinhlanganisela zinesithembiso njengamakhambi emvelo okukhuthaza impilo yonke nokuphila kahle.

Izithenjwa
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