I-Stephania Extract Cepharanthine Powder
I-Stephania Extract I-Cepharanthine Powder iyisithako esithathwe ezigabeni zesitshalo i-Stephania cephalantha Hayata (Stephania japonica （Thunb.） Miers) noma i-Stephania epigaea Lo/ Stephania yunnanensis HSLo. I-Cepharanthine iwumkhiqizo wemvelo ohlukaniswe kulesi sitshalo futhi ibilokhu ifundwa ngezifundo ezahlukahlukene ngenxa yezakhiwo zayo ezingaba khona kwezokwelapha. Kutholakale ukuthi ibonisa imisebenzi yokulwa ne-SARS-CoV-2, ikhombisa ukusebenza kahle ekucindezeleni ukwanda kwegciwane. Ngaphezu kwalokho, i-Cepharanthine ibonise ikhono lokuguqula ukumelana nemithi eminingi okubangelwa yi-P-glycoprotein (P-gp) emaseli athile futhi ithuthukise ukuzwela kwama-anticancer agents kumamodeli okuhlola. Ngaphezu kwalokho, kuboniswe ukuthi inemiphumela yokuvimbela kuma-enzyme e-cytochrome P450 esibindi somuntu i-CYP3A4, CYP2E1, kanye ne-CYP2C9, futhi ihlotshaniswa nemiphumela yokulwa nomdlavuza, ukuvuvukala, kanye nokuvimbela umdlavuza.
Ngamafuphi, i-Stephania Extract Cepharanthine Powder iwuhlobo lwempuphu lomkhiqizo wemvelo i-Cepharanthine ethathwe esitshalweni i-Stephania cephalantha, esiye sabonakala sinamandla ezinhlotsheni ezahlukene zemithi.
| Umkhiqizo | I-Cepharanthine |
| I-CAS | 481-49-2 |
| Ukuhlolwa | 80%~99% |
| Ukubukeka | Impuphu emhlophe |
| Ukupakisha | Isikhwama se-1KG/Foyili |
| Into | Imininingwane |
| Ukubukeka | i-powder emhlophe empunga, iphunga elingathathi hlangothi, i-hygroscopic kakhulu |
| Ukuhlonza | I-TLC: Isixazululo esijwayelekile kanye nesisombululo sokuhlola indawo efanayo, i-RF |
| Ukuhlolwa (Isisekelo Esomile) | 98.0%--102.0% |
| I-Optical Eqondile | -2.4°~ -2.8° |
| PH | 4.5~7.0 |
| Izinsimbi Ezisindayo (Njengo-Pb) | ≤10ppm |
| As | ≤1ppm |
| Pb | ≤0.5ppm |
| Cd | ≤1ppm |
| Hg | ≤0.1ppm |
| Into ehlobene | Ibala elingekho likhulu kunebala lesisombululo elijwayelekile |
| Isinyibilikisi esisele | <0.5% |
| Okuqukethwe kwamanzi | <2% |
I-Stephania Extract Cepharanthine Powder iwumkhiqizo wemvelo othathwe esitshalweni i-Stephania cephalantha Hayata. Kutholakale ukuthi inezakhiwo eziningana zemithi, okuhlanganisa:
1. Imisebenzi yokulwa ne-SARS-CoV-2
2. Imiphumela yokuvimbela ekwandeni kwegciwane
3. Ukuguqulwa kokumelana nemithi eminingi okubangelwa yi-P-glycoprotein
4. Ukuthuthukiswa kokuzwela ezintweni ezilwa nomdlavuza
5. Imiphumela yokuvimbela kuma-enzyme e-cytochrome P450 esibindi somuntu i-CYP3A4, i-CYP2E1, kanye ne-CYP2C9
6. Imiphumela yokulwa nomdlavuza, ukuvuvukala, kanye nokuvimbela umdlavuza
Ukwenziwa kwe-cephalanthine ku-Stephania kuqala ngokujiya kwe-dopamine kanye ne-4-hydroxyphenylacetaldehyde (4-HPAA, 5) nge-norcoclaurine synthase (NCS), okuveza i-norcoclaurine.
I-Cepharanthine iyancibilika ezinyibilikisini eziphilayo ezifana ne-ethanol, i-DMSO, kanye ne-dimethyl formamide (DMF). Ukuncibilika kwe-cephalanthine kulezi zinyibilikisi cishe ku-2, 5, kanye no-10 mg/ml, ngokulandelana. I-Cepharanthine ayincibiliki kakhulu ezingxubeni zamanzi.
Izimboni zokusetshenziswa kwe-Stephania Extract Cepharanthine Powder zifaka phakathi i-Pharmaceutical, Nutraceutical, Biotechnology, kanye ne-Herbal Medicine, izinhlelo zokusebenza eziyinhloko yilezi ezilandelayo:
Ukusetshenziswa okungenzeka ekwelashweni kwe-antiviral
Kungenzeka kube yisithasiselo ekwelapheni umdlavuza
Kungenzeka ukusetshenziswa ekwelapheni ukuvuvukala
Kungenzeka ukuthi uyisithako esidambisa ubuhlungu
Lezi zinhlelo zokusebenza ziqokomisa ukusetshenziswa okuhlukahlukene okungenzeka kwe-Stephania Extract Cepharanthine Powder ezimweni ezahlukene zokwelapha.
Ukupakisha Nesevisi
Ukupakisha
* Isikhathi Sokulethwa: Cishe izinsuku zokusebenza ezi-3-5 ngemuva kokukhokha kwakho.
* Iphakheji: Kuma-drum e-fiber anezikhwama ezimbili zepulasitiki ngaphakathi.
* Isisindo Esiphelele: 25kgs/isigubhu, Isisindo Esiphelele: 28kgs/isigubhu
* Usayizi Wesigubhu Nomthamo: ID42cm × H52cm, 0.08 m³/ Isigubhu
* Indawo Yokugcina: Igcinwe endaweni eyomile nepholile, gcina kude nokukhanya okunamandla nokushisa.
* Impilo Yeshelufu: Iminyaka emibili uma igcinwe kahle.
Ukuthunyelwa
* I-DHL Express, i-FEDEX, kanye ne-EMS ngamanani angaphansi kuka-50KG, ngokuvamile abizwa ngokuthi isevisi ye-DDU.
* Ukuthunyelwa ngemikhumbi ngamanani angaphezu kwama-500 kg; kanye nokuthunyelwa ngendiza ngama-50 kg ngaphezulu.
* Ngemikhiqizo enenani eliphezulu, sicela ukhethe ukuthunyelwa ngendiza kanye ne-DHL express ukuze kuphephe.
* Sicela uqinisekise ukuthi ungakwazi yini ukugcwalisa izimpahla uma zifika emasimini akho ngaphambi kokufaka i-oda. Kubathengi abavela eMexico, eTurkey, e-Italy, eRomania, eRussia, nakwezinye izindawo ezikude.
Izindlela Zokukhokha Nokulethwa
I-Express
Ngaphansi kwe-100kg, Izinsuku ezi-3-5
Isevisi yokungena emnyango kulula ukuyithatha izimpahla
Ngasolwandle
Ngaphezulu kwama-300kg, cishe izinsuku ezingama-30
Kudingeka umthengisi wezinsizakalo zokukhishwa kwemvume ochwepheshe
Ngomoya
100kg-1000kg, Izinsuku ezi-5-7
Kudingeka umthengisi wezinsizakalo zokuhlanza ochwepheshe kusukela esikhumulweni sezindiza kuya esikhumulweni sezindiza
Imininingwane Yokukhiqiza (Ishadi Lokugeleza)
1. Ukuthola Nokuvuna
2. Ukukhipha
3. Ukugxila Nokuhlanzwa
4. Ukomisa
5. Ukulinganisa
6. Ukulawulwa Kwekhwalithi
7. Ukupakisha 8. Ukusatshalaliswa
Isitifiketi
It iqinisekiswe yizitifiketi ze-ISO, HALAL, kanye ne-KOSHER.
