I-Vinca Rosea Extract Vincristine
I-Vinca Rosea Extract Vincristine ibhekisela kwinhlanganisela yemithi i-Vincristine, etholakala esitshalweni se-periwinkle (Vinca rosea), eyaziwa nangokuthi Catharanthus roseus, amehlo akhanyayo, i-Cape periwinkle, isitshalo samathuna, i-periwinkle yase-Madagascar, incekukazi endala, i-pink periwinkle, i-rose. I-periwinkle, uhlobo olungapheli lwesitshalo esiqhakaza emndenini we-Apocynaceae.
I-Vincristine iyi-alkaloid yemvelo futhi isetshenziswa njengomuthi we-chemotherapy ukwelapha izinhlobo ezahlukene zomdlavuza, okuhlanganisa i-leukemia, i-lymphoma, nezimila eziqinile. Isebenza ngokuphazamisa ukukhula kwamangqamuzana omdlavuza.
| Izithako Eziyinhloko Ezisebenzayo ngesi-Chinese | Igama lesiNgisi | Inombolo ye-CAS. | Isisindo samangqamuzana | I-Molecular Formula |
| 长春胺 | I-Vincamine | 1617-90-9 | 354.44 | I-C21H26N2O3 |
| 脱水长春碱 | I-Anhydrovinblastine | 38390-45-3 | 792.96 | I-C46H56N4O8 |
| 異長春花苷內酰胺 | I-Strictosamide | 23141-25-5 | 498.53 | I-C26H30N2O8 |
| 四氢鸭脚木碱 | I-Tetrahydroalstonine | 6474-90-4 | 352.43 | I-C21H24N2O3 |
| 酒石酸长春瑞滨 | I-Vinorelbine Tartrate | 125317-39-7 | 1079.12 | C45H54N4O8.2(C4H6O6);C |
| 长春瑞滨 | I-Vinorelbine | 71486-22-1 | 778.93 | I-C45H54N4O8 |
| 长春新碱 | I-Vincristine | 57-22-7 | 824.96 | I-C46H56N4O10 |
| 硫酸长春新碱 | I-Vincristine sulfate | 2068-78-2 | 923.04 | I-C46H58N4O14S |
| 硫酸长春质碱 | I-Catharanthine sulfate | 70674-90-7 | 434.51 | I-C21H26N2O6S |
| 酒石酸长春质碱 | I-Catharanthine hemitartrate | 4168-17-6 | 486.51 | I-C21H24N2O2.C4H6O6 |
| 长春花碱 | I-Vinblastine | 865-21-4 | 810.99 | I-C46H58N4O9 |
| 长春质碱 | I-Catharanthini | 2468-21-5 | 336.43 | I-C21H24N2O2 |
| 文朵灵 | I-Vindoline | 2182-14-1 | 456.53 | I-C25H32N2O6 |
| 硫酸长春碱 | I-Vinblastine sulfate | 143-67-9 | 909.05 | I-C46H60N4O13S |
| β-谷甾醇 | I-β-Sitosterol | 83-46-5 | 414.71 | I-C29H50O |
| 菜油甾醇 | I-Camperol | 474-62-4 | 400.68 | C28H48O |
| 齐墩果酸 | I-oleanolic acid | 508-02-1 | 456.7 | I-C30H48O3 |
| IMIKHIQIZO YOMKHIQIZO | ||
| Igama Lomkhiqizo: | I-Vinca rosea inembile | |
| Igama Lebhotani: | I-Catharanthus roseus (L.) | |
| Ingxenye yesitshalo | Imbali | |
| Izwe azalelwe kulo: | China | |
| HLAZIYA IZINTO | INKCAZO | INDLELA YOKUHLOLA |
| Ukubukeka | Impushana emihle | I-Organoleptic |
| Umbala | Impushana ensundu ensundu | Okubonakalayo |
| Iphunga & Ukunambitha | Isici | I-Organoleptic |
| Ukuhlonza | Ifana nesampula ye-RS | HPTLC |
| Khipha Isilinganiso | 4:1–20:1; I-Vincristine 98% min | |
| Sieve Analysis | 100% nge-80 mesh | I-USP39 <786> |
| Ukulahlekelwa ekomisweni | ≤ 5.0% | I-Eur.Ph.9.0 [2.5.12] |
| Umlotha Ophelele | ≤ 5.0% | I-Eur.Ph.9.0 [2.4.16] |
| Ukuhola (Pb) | ≤ 3.0 mg/kg | I-Eur.Ph.9.0<2.2.58>ICP-MS |
| I-Arsenic (As) | ≤ 1.0 mg/kg | I-Eur.Ph.9.0<2.2.58>ICP-MS |
| I-Cadmium(Cd) | ≤ 1.0 mg/kg | I-Eur.Ph.9.0<2.2.58>ICP-MS |
| I-Mercury(Hg) | ≤ 0.1 mg/kg -Reg.EC629/2008 | I-Eur.Ph.9.0<2.2.58>ICP-MS |
| Insimbi enzima | ≤ 10.0 mg/kg | I-Eur.Ph.9.0<2.4.8> |
| Izincibilikisi Ezisele | Conform Eur.ph. 9.0 <5,4 > kanye ne-EC European Directive 2009/32 | I-Eur.Ph.9.0<2.4.24> |
| Izinsalela zezibulala-zinambuzane | Conform Regulations(EC) No.396/2005okuhlanganisa izijobelelo nezibuyekezo ezilandelanayo Reg.2008/839/CE | I-Chromatography yegesi |
| Amagciwane e-Aerobic (TAMC) | ≤10000 cfu/g | I-USP39 <61> |
| Imvubelo/Isikhunta(TAMC) | ≤1000 cfu/g | I-USP39 <61> |
| I-Escherichia coli: | Ayikho ku-1g | I-USP39 <62> |
| I-Salmonella spp: | Akukho ngo-25g | I-USP39 <62> |
| I-Staphylococcus aureus: | Ayikho ku-1g | |
| I-Listeria Monocytogenens | Akukho ngo-25g | |
| I-Aflatoxins B1 | ≤ 5 ppb -Reg.EC 1881/2006 | I-USP39 <62> |
| Ama-Aflatoxins ∑ B1, B2, G1, G2 | ≤ 10 ppb -Reg.EC 1881/2006 | I-USP39 <62> |
Izici zomkhiqizo we-Vinca Rosea Extract Vincristine zingabandakanya:
Ukuhlanzeka okuphezulu:Imikhiqizo ye-Vincristine ivamise ukuba nokuhlanzeka okuphezulu futhi ithobela izindinganiso eziqinile zokwenziwa kwezidakamizwa ukuze kuqinisekiswe ukuhlanzeka nokuzinza komuthi.
Ukulandelelwa komthombo:I-Vincristine ivame ukukhishwa esitshalweni se-Catharanthus roseus. Inqubo yokukhiqiza yayo iyalandeleka futhi ihambisana nokuqoqwa nokukhiqizwa kwezinto zomuthi we-botanical.
Ukuzinza kwamakhemikhali:Njengenhlanganisela ye-alkaloid, i-vincristine inokusimama okuhle kwamakhemikhali futhi ifanele ukukhiqizwa kwemithi nokugcinwa isikhathi eside.
Umsebenzi wokulwa nesimila:Njengesidakamizwa esilwa ne-tumor, i-vincristine inomsebenzi wokuvimbela ukukhula nokusabalala kwamangqamuzana e-tumor futhi ifanele ukwelashwa komdlavuza ohlukahlukene.
Ukuqinisekiswa komtholampilo:I-Vincristine iqinisekiswe ngokomtholampilo futhi isetshenziswa kabanzi emisebenzini yezokwelapha, ngokusekelwa okuthembekile kwedatha yomphumela wezokwelapha kanye nomphumela womtholampilo.
Lezi zici zomkhiqizo zigqamisa ikhwalithi, umsebenzi, kanye nenani lomtholampilo le-vincristine njengomuthi obalulekile wokulwa nomdlavuza.
I-Vinca Rosea Extract Vincristine yaziwa ngokuyinhloko ngokusetshenziswa kwayo kwezemithi ekwelapheni umdlavuza futhi ayivamisile ukuhlotshaniswa nezinzuzo zezempilo eziqondile zokusetshenziswa komthengi okuvamile. I-Vincristine, etholakala esitshalweni i-Vinca rosea, iwumuthi onamandla we-chemotherapy osetshenziselwa ukwelapha izinhlobo ezihlukahlukene zomdlavuza, okuhlanganisa i-leukemia, i-lymphoma, nezimila eziqinile. Isebenza ngokuphazamisa ukukhula kwamangqamuzana omdlavuza.
Kubalulekile ukuqaphela ukuthi i-Vincristine iwumuthi kadokotela onikezwa ngaphansi kokuqondisa kochwepheshe bezempilo, futhi ukusetshenziswa kwawo kuhlotshaniswa nemiphumela engemihle engase ibe khona kanye nezingozi. Ngakho-ke, ngokuvamile ayimakethwa noma isetshenziswe ngezinzuzo zayo zezempilo ngaphandle kwezilungiselelo zomtholampilo.
Izicelo ezinemininingwane ye-Vinca Rosea Extract Vincristine zifaka:
Ukwelashwa komdlavuza:I-Vincristine isetshenziswa ngokuyinhloko ekwelapheni izinhlobo ezahlukene zomdlavuza, okuhlanganisa i-leukemia, i-lymphoma, nezimila eziqinile. Isetshenziswa njengengxenye yemithi yokwelapha ngamakhemikhali ukuze ivimbele ukukhula kwamangqamuzana omdlavuza.
Ucwaningo Lwezemithi:I-extract isetshenziswa ocwaningweni lwezemithi ukuze kuthuthukiswe izindlela zokwelapha ezintsha zomdlavuza kanye nocwaningo lwendlela yokusebenza kwayo.
Ikhemistri Yezokwelapha:I-Vincristine isebenza njengenhlanganisela ebalulekile emkhakheni wamakhemikhali emithi, efaka isandla ekwakhiweni kwezidakamizwa ezintsha kanye nama-ejenti okwelapha.
I-Biotechnology:I-extract ingase isetshenziswe ezinhlelweni ze-biotechnological, ezifana nokukhiqizwa kwezakhi ezilwa nomdlavuza kanye nezinhlelo zokulethwa kwezidakamizwa.
Izilingo Zomtholampilo:I-Vincristine ihileleke ezivivinyweni zomtholampilo ukuze ihlole ukusebenza kwayo ekwelapheni izinhlobo ezihlukahlukene zomdlavuza kanye nokuphenya okungenzeka kube izicelo kwezinye izimo zezokwelapha.
Ukwakhiwa Kwezidakamizwa:I-extract isetshenziswa ekwakhiweni kwemikhiqizo yezemithi, okuhlanganisa izixazululo ezijovwayo nezinye izinhlobo zemithamo yokwelapha umdlavuza.
Lezi zinhlelo zokusebenza zibonisa ukusetshenziswa okuhlukahlukene kwe-Vinca Rosea Extract Vincristine ekwelapheni umdlavuza, ucwaningo lwezemithi, kanye nokuthuthukiswa kwezidakamizwa.
I-Vincristine iwumuthi onamandla we-chemotherapy, futhi ukusetshenziswa kwawo kungahlotshaniswa nemiphumela engemihle eminingana engaba khona. Eminye yemiphumela emibi engaba khona ye-Vincristine powder ingabandakanya:
I-Neurotoxicity:I-Vincristine ingabangela ukulimala ohlelweni lwezinzwa lwe-peripheral, okuholela ezimpawu ezifana nokuba ndikindiki, ukushoshozela, nobuthakathaka emaphethelweni.
Imiphumela Yamathumbu:Imiphumela emibi evamile yesisu ingase ihlanganise isicanucanu, ukuhlanza, ukuqunjelwa, nobuhlungu besisu.
Ukucindezelwa komnkantsha:I-Vincristine ingacindezela umnkantsha, okuholela ekwehleni kokukhiqizwa kwamangqamuzana egazi, okungase kubangele i-anemia, ukwanda kokungenwa izifo, kanye nokuthambekela ukopha.
Ukuqothuka kwezinwele:Abanye abantu bangase babe nokulahlekelwa izinwele noma ukuncipha kwezinwele ngenxa yokwelashwa kwe-Vincristine.
Ubuhlungu bomhlathi:I-Vincristine ingabangela uhlobo oluthile lobuhlungu olwaziwa ngokuthi "i-vincristine-induced neuropathy-acute-onset," ebonakala ngobuhlungu bomhlathi nobunzima bokugwinya.
Eminye imithelela engaba khona:Imiphumela engemihle eyengeziwe ingase ihlanganise ubuthakathaka bemisipha, izinguquko kumfutho wegazi, nokungezwani komzimba.
Kubalulekile ukuqaphela ukuthi uhlu olungenhla aluphelele, futhi ochwepheshe bezokunakekelwa kwempilo kufanele baqaphe eduze abantu abathola i-Vincristine nganoma yimiphi imiphumela emibi engaba khona. Imiphumela ethile engemihle kanye nokuqina kwayo kungahluka kumuntu nomuntu. Iziguli kufanele zixoxe ngemiphumela emibi engaba khona kanye nokukhathazeka nomhlinzeki wazo wezempilo ngaphambi kokuqala ukwelashwa kwe-Vincristine.
Ukupakisha Nesevisi
Ukupakisha
* Isikhathi Sokulethwa: Cishe izinsuku zokusebenza ezi-3-5 ngemuva kokukhokha kwakho.
* Iphakheji: Kuzigubhu zefayibha ezinezikhwama zepulasitiki ezimbili ngaphakathi.
* Isisindo Net: 25kgs/drum, Isisindo Esiphelele: 28kgs/Drum
* Usayizi Wesigubhu & Nomthamo: ID42cm × H52cm, 0.08 m³/ Isigubhu
* Isitoreji: Kugcinwe endaweni eyomile nepholile, gwema ukukhanya okunamandla nokushisa.
* Impilo yeshelufu: Iminyaka emibili uma igcinwe kahle.
Ukuthumela ngomkhumbi
* I-DHL Express, i-FEDEX, ne-EMS ngamanani angaphansi kuka-50KG, ngokuvamile abizwa ngokuthi isevisi ye-DDU.
* Ukuthunyelwa kolwandle ngamanani angaphezu kwama-500 kg; futhi ukuthunyelwa ngomoya kuyatholakala nge-50 kg ngaphezulu.
* Ngemikhiqizo yenani eliphezulu, sicela ukhethe ukuthunyelwa ngomoya kanye ne-DHL express ukuze uphephe.
* Sicela uqinisekise ukuthi ungakwazi yini ukwenza imvume lapho izimpahla zifika kumasiko akho ngaphambi kokufaka i-oda. Kubathengi abavela eMexico, Turkey, Italy, Romania, Russia, nezinye izindawo ezikude.
Izindlela Zokukhokha Nezokudiliva
Express
Ngaphansi kwe-100kg, Izinsuku ezingu-3-5
Isevisi yendlu ngendlu kulula ukuthatha izimpahla
Ngasolwandle
Over 300kg, Cishe izinsuku ezingu-30
Kudingeka ichweba eliya esikhungweni somdayiseli wokuthola imvume
Ngomoya
100kg-1000kg, 5-7 Izinsuku
Kudingeka umthengisi wemvume yochwepheshe wesikhumulo sezindiza oya esikhumulweni sezindiza
Imininingwane Yokukhiqiza (Ishadi Eligelezayo)
1. Ukutshala Nokuvuna
2. Isizinda
3. Ukugxila kanye Nokuhlanzwa
4. Ukomisa
5. Ukumisa
6. Ukulawulwa Kwekhwalithi
7. Ukupakisha 8. Ukusabalalisa
Isitifiketi
It iqinisekiswa yi-ISO, HALAL, nezitifiketi ze-KOSHER.
