I-Vinca Rosea Extract Vincrintine
I-Vinca Rosea Extract Vincrintine isho i-vincristic yezemithi, ethathwe kwiPeriwinkle Plant (Vinca Rosea), eyaziwa nangokuthi i-madagascar periwinkle, i-Pink Periwinkle, i-Pink Periwinkle, iyizinhlobo zezimbali ezindala emndenini emndenini emndenini womndeni Apocynaceae.
I-VinCrintine iyi-alkaloid yemvelo futhi isetshenziswa njengomuthi we-chemotherapy ukwelapha izinhlobo ezahlukahlukene zomdlavuza, kufaka phakathi i-leukemia, i-lymphoma, kanye nama-tumors aqinile. Isebenza ngokuphazamisa ukukhula kwamaseli womdlavuza.
| Izithako eziphambili ezisebenzayo ngesiShayina | Igama lesiNgisi | Case No. | Isisindo molecular | Ifomula yamangqamuzana |
| 长春胺 | Iphini levincamine | 1617-90-9 | 354.44 | C21h26NN2O3 |
| 脱水长春碱 | Anhydrovinblastine | 38390-45-3 | 792.96 | C46h56n4o8 |
| 異長春花苷內酰胺 | I-Stricesamide | 23141-25-5-5 | 498.53 | C26h30n2o8 |
| 四氢鸭脚木碱 | Tetrahydronine | 6474-90-4 | 352.43 | C21h24NNO3 |
| 酒石酸长春瑞滨 | IVinorelbine tartrate | 125317-39-7 | 1079.12 | C4hh54n4o8.2 (c4h6o6); c |
| 长春瑞滨 | VinoRelbine | 71486-22-1 | 778.93 | C4hh54n4o8 |
| 长春新碱 | Vincritine | 57-22-7-7 | 824.96 | C46h56n4o10 |
| 硫酸长春新碱 | Vincrintine sulfate | 2068-78-2 | 923.04 | C46h58n4o14s |
| 硫酸长春质碱 | Catharanthine sulfate | 70674-90-7 | 434.51 | C21h26NNO6S |
| 酒石酸长春质碱 | Catharanthine Hemitartrate | 4168-17-6-6 | 486.51 | C21h24N2O2.c4h6o6 |
| 长春花碱 | Vinblastine | 865-21-4 | 810.99 | C46h58n4o9 |
| 长春质碱 | Catharanthine | 2468-21-5 | 336.43 | C21h24NN2O2 |
| 文朵灵 | Uhlaka | 2182-14-1 | 456.53 | C25h32N2O6 |
| 硫酸长春碱 | Vinblastine sulfate | 143-67-9 | 909.05 | C46h60n4o13s |
| β- 谷甾醇 | β-sitololtol | 83-46-5 | 414.71 | C29h50o |
| 菜油甾醇 | Iphethini kahulumeni | 474-62-4 | 400.68 | C28h48o |
| 齐墩果酸 | I-Oleanolic acid | 508-02-1 | 456.7 | C30h48o3 |
| Ukucaciswa komkhiqizo | ||
| Igama lomkhiqizo: | I-Vinca Rosea iyakwazi | |
| Igama le-Botanic: | Catharanthus Roseus (L.) | |
| Ingxenye yesitshalo | Umqhakazo | |
| Izwe azalelwe kulo: | Izitsha zokudlela zebumba uqobo | |
| Izinto Zokuhlaziya | Ukucacisa | Indlela yokuhlola |
| Ukubonakala | Umdanso omuhle | Okomshini |
| Umbala | I-brown icon powder | Phathelene nokubona |
| Iphunga nokunambitha | -Yisimilo | Okomshini |
| Ukukhonjwa | Kufana nesampula ye-RS | I-HPTLC |
| Khipha isilinganiso | 4: 1 ~ 20: 1; Vincrintine 98% min | |
| Ukuhlaziywa kwesihlungo | I-100% nge-80 mesh | I-US39 <786> |
| Ukulahleka kokuwomile | ≤ 5.0% | I-EUR.PH.9.0 [2.5.12] |
| Inani eliphelele | ≤ 5.0% | I-EUR.PH.9.0 [2.4.16] |
| Ukuhola (PB) | ≤ 3.0 mg / kg | I-EUR.PH.9.0 <2.2.58> ICP-MS |
| I-Arsenic (as) | ≤ 1.0 mg / kg | I-EUR.PH.9.0 <2.2.58> ICP-MS |
| I-Cadmium (CD) | ≤ 1.0 mg / kg | I-EUR.PH.9.0 <2.2.58> ICP-MS |
| I-Mercury (HG) | ≤ 0.1 Mg / kg -reg.ec629 / 2008 | I-EUR.PH.9.0 <2.2.58> ICP-MS |
| Insimbi esindayo | ≤ 10.0 MG / KG | I-EUR.PH.9.0 <2.4.8> |
| I-Solvents insurents | Ukuvumelana kwe-EUR.ph. 9.0 <5,4> kanye ne-EC Europee Directive 2009/32 | I-EUR.PH.9.0 <2.4.24> |
| Izinsalela zokubulala izinambuzane | Imithethonqubo evumelana (EC) NO.396 / 2005Inccuding AWNSEBS kanye nezibuyekezo ezilandelanayo Reg.2008 / 839 / CE | Igesi i-chromatography |
| I-Aerobic bacteria (Tamc) | ≤10000 cfu / g | Usp39 <61> |
| I-Yeast / isikhunta (Tamc) | ≤1000 cfu / g | Usp39 <61> |
| U-Escherhihia Coli: | Akekho ku-1g | Usp39 <62> |
| ISalmonella SPP: | Akekho ku-25g | Usp39 <62> |
| Staphylococcus aureus: | Akekho ku-1g | |
| Listeria monocytogenens | Akekho ku-25g | |
| I-Aflatoxins B1 | ≤ 5 PPB -REG.EC 1881/2006 | Usp39 <62> |
| I-Aflatoxins σ B1, B2, G1, G2 | ≤ 10 ppb -reg.ec 1881/2006 | Usp39 <62> |
Izici zomkhiqizo zeVinA Rosea Extract Vincristine zingafaka:
Ukumsulwa okuphezulu:Imikhiqizo yeVincrintic ivame ukuba nobumsulwa obuphezulu futhi ithobele amazinga aqinile wokukhiqiza izidakamizwa ukuze aqinisekise ubumsulwa nokuqina kwesidakamizwa.
Ukulandelela Umthombo:I-Vincrintin ivame ukukhishwa kwi-Catharanthus Roseus Plant. Inqubo yayo yokukhiqiza iyalandeleka futhi ihambisana nokuqoqwa kanye nokucaciswa kokukhiqizwa kwezinto zokwelapha ze-botanical.
Ukuqina kwamakhemikhali:Njenge-alkalioid Compound, i-vincrintin inokuqina okuhle kwamakhemikhali futhi ilungele ukukhiqizwa kwemithi kanye nesitoreji eside.
Umsebenzi we-Anti-Tumor:Njengesidakamizwa se-anti-stumar, i-vincrintine inomsebenzi wokuvimbela ukukhula kanye nokusabalala kwamaseli we-tumor futhi ilungele ukwelashwa komdlavuza ohlukahlukene.
Ukuqinisekiswa Kwemitholampilo:I-Vincrintin iqinisekiswe ngokomtholampilo futhi isetshenziswa kabanzi ekusebenzeni kwezokwelapha, ngokusekelwa kokwenziwa kwemithi nokwenziwa kwemitholampilo.
Lezi zici zomkhiqizo ziqokomisa ikhwalithi, umsebenzi, kanye nenani lomtholampilo le-vincrintine njengomuthi obalulekile wokulwa nomdlavuza.
I-Vinca Rosea Extract Vincrintine yaziwa ngokuyinhloko ngezicelo zayo ezenzakade ekwelashweni komdlavuza futhi ayihambelani nemihlomulo yezempilo eqondile yokusetshenziswa kwabathengi okujwayelekile. I-Vincrintine, ethathwe ku-Vinca Rosea Plant, umuthi onamandla we-chemotherapy esetshenziselwa ukwelapha izinhlobo ezahlukene zomdlavuza, kufaka phakathi i-leukemia, i-lymphoma, kanye nama-tumors aqinile. Isebenza ngokuphazamisa ukukhula kwamaseli womdlavuza.
Kubalulekile ukuqaphela ukuthi i-vincrintine umuthi onikezwe umuthi ophathwe ngaphansi kokugadwa kochwepheshe bezokunakekelwa kwempilo, futhi ukusetshenziswa kwawo kuhlotshaniswa nemiphumela emibi nezinceku. Ngakho-ke, akukhangiswa ngokujwayelekile noma kudliwe ngezinzuzo zalo zezempilo ngaphandle kwezilungiselelo zomtholampilo.
Ukusetshenziswa okuningiliziwe kwe-Vinca Rosea Extract Vincristine kufaka phakathi:
Ukwelashwa komdlavuza:I-Vincrintine isetshenziswa ngokuyinhloko ekwelapheni izinhlobo ezahlukahlukene zomdlavuza, kufaka phakathi i-leukemia, i-lymphoma, kanye nama-tumors aqinile. Iphathwe njengengxenye yama-regimens e-chemotherapy ukuvimbela ukukhula kwamaseli womdlavuza.
Ucwaningo lwezemithi:Ukukhishwa kusetshenziselwa ucwaningo lwezemithi ekuthuthukisweni kokwelashwa okusha komdlavuza kanye nocwaningo lwendlela yalo yesenzo.
Amakhemikhali wezokwelapha:IVincrintint isebenza njengengxenye ebalulekile emkhakheni wamakhemikhali wezokwelapha, ifaka isandla ekwakhiweni kwezidakamizwa zenoveli nabezokwelapha abahlinzeki.
I-Biotechnology:Ukukhishwa kungaqashwa kwizicelo ze-biotechnological, njengokukhiqizwa kwemisakazo ye-anticancer kanye nezinhlelo zokulethwa kwezidakamizwa.
Izilingo Zomtholampilo:UVincrintine ubandakanyeka ekuvivinyweni kwemitholampilo ukuhlola ukusebenza kwawo ngokuphatha izinhlobo ezahlukahlukene zomdlavuza kanye nokuphenya izinhlelo zokusebenza ezingaba khona kwezinye izimo zezokwelapha.
Ukwakhiwa kwezidakamizwa:Ukukhishwa kusetshenziswa ekwakhiweni kwemikhiqizo yezemithi, kufaka phakathi izixazululo ezijova kanye nezinye izinhlobo zemithamo yokwelashwa komdlavuza.
Lezi zinhlelo zokusebenza zibonisa ukusetshenziswa okuhlukahlukene kwe-vinca rosea ekhipha i-vincrintine ekwakheni umdlavuza, ucwaningo lwemithi kanye nokuthuthukiswa kwezidakamizwa.
I-Vincrintin ingumuthi onamandla we-chemotherapy, futhi ukusetshenziswa kwayo kungahlotshaniswa nemiphumela emibi eminingana engaba khona. Eminye yemiphumela emibi engaba khona ye-vincrintint powder ingafaka:
I-Neurotoxicity:I-Vincrintin ingadala umonakalo ohlelweni lwezinzwa oluphelele, okuholela ezimpawuni ezinjengokukhubazeka, ukudonsa kanye nobuthakathaka emaphethelweni.
Imiphumela yesisu:Imiphumela emibi ye-gastroyestinal emibi ingafaka isicanucanu, ukugabha, ukuqunjelwa kanye nobuhlungu besisu.
Ukucindezela Komugqa Wethambo:IVincristine ingacindezela umongo wethambo, okuholela ekunciphiseni ukukhiqizwa kwamangqamuzana egazi, okungahle kube nomphumela we-anemia, ukwengeza ukuthambekela kwezifo, nokuthambekela kokopha.
Ukulahleka kwezinwele:Abanye abantu bangathola ukulahleka kwezinwele noma ukuncipha kwezinwele ngenxa yokwelashwa kwe-vincrintic.
Imihlathi Ubuhlungu:I-Vincrintin ingadala uhlobo oluthile lobuhlungu olwaziwa ngokuthi "i-neuropathy-acute-acute inyuty," elibonakala ngobuhlungu emhlathini nobunzima bokugwinya.
Eminye imiphumela engaba khona:Imiphumela emibi engezekile ingafaka ubuthakathaka bemisipha, izinguquko emfutho yegazi, nokusabela komzimba.
Kubalulekile ukuqaphela ukuthi uhlu olungenhla alupheli, futhi ochwepheshe bezokunakekelwa kwempilo kufanele baqaphe kakhulu abantu abathola i-vincrintine nganoma yimiphi imiphumela emibi engaba khona. Imiphumela ethile emibi futhi ubulukhuni bayo buhlukahluka kuye kumuntu. Iziguli kufanele zixoxe ngemiphumela emibi nokukhathazeka nomuntu ohlinzeka ngezempilo ngaphambi kokuqala ukwelashwa kwe-vincrintine.
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