I-Vinca Rosea Extract Vincristine
I-Vinca Rosea Extract I-Vincristine ibhekisela ekwakhiweni kwemithi i-Vincristine, etholakala esitshalweni se-periwinkle (i-Vinca rosea), esaziwa nangokuthi i-Catharanthus roseus, amehlo akhanyayo, i-Cape periwinkle, isitshalo samathuna, i-Madagascar periwinkle, i-old maid, i-pink periwinkle, i-rose periwinkle, uhlobo lwesitshalo esiqhakaza njalo emndenini we-Apocynaceae.
I-Vincristine iyi-alkaloid yemvelo futhi isetshenziswa njengomuthi we-chemotherapy ukwelapha izinhlobo ezahlukene zomdlavuza, okuhlanganisa i-leukemia, i-lymphoma, kanye nezimila eziqinile. Isebenza ngokuphazamisa ukukhula kwamaseli omdlavuza.
| Izithako Eziyinhloko Ezisebenzayo ngesiShayina | Igama lesiNgisi | Inombolo ye-CAS | Isisindo sama-molecule | Ifomula Yamamolekyuli |
| 长春胺 | I-Vincamine | 1617-90-9 | 354.44 | C21H26N2O3 |
| 脱水长春碱 | I-Anhydrovinblastine | 38390-45-3 | 792.96 | C46H56N4O8 |
| 異長春花苷內酰胺 | I-Strictosamide | 23141-25-5 | 498.53 | C26H30N2O8 |
| 四氢鸭脚木碱 | I-Tetrahydroalstoneine | 6474-90-4 | 352.43 | C21H24N2O3 |
| 酒石酸长春瑞滨 | I-Vinorelbine Tartrate | 125317-39-7 | 1079.12 | C45H54N4O8.2(C4H6O6);C |
| 长春瑞滨 | I-Vinorelbine | 71486-22-1 | 778.93 | C45H54N4O8 |
| 长春新碱 | UVincristine | 57-22-7 | 824.96 | C46H56N4O10 |
| 硫酸长春新碱 | I-Vincristine sulfate | 2068-78-2 | 923.04 | C46H58N4O14S |
| 硫酸长春质碱 | I-Catharanthine Sulfate | 70674-90-7 | 434.51 | C21H26N2O6S |
| 酒石酸长春质碱 | I-Catharanthine hemitartrate | 4168-17-6 | 486.51 | C21H24N2O2.C4H6O6 |
| 长春花碱 | I-Vinblastine | 865-21-4 | 810.99 | C46H58N4O9 |
| 长春质碱 | I-Catharanthine | 2468-21-5 | 336.43 | C21H24N2O2 |
| 文朵灵 | I-Vindoline | 2182-14-1 | 456.53 | C25H32N2O6 |
| 硫酸长春碱 | I-Vinblastine Sulfate | 143-67-9 | 909.05 | C46H60N4O13S |
| β-谷甾醇 | i-β-Sitosterol | 83-46-5 | 414.71 | C29H50O |
| 菜油甾醇 | I-Campesterol | 474-62-4 | 400.68 | C28H48O |
| 齐墩果酸 | I-Oleanolic acid | 508-02-1 | 456.7 | C30H48O3 |
| IMINININGWANE YOMKHIQIZO | ||
| Igama Lomkhiqizo: | I-Vinca rosea eqondile | |
| Igama Lezitshalo: | I-Catharanthus roseus (L.) | |
| Ingxenye yesitshalo | Imbali | |
| Izwe azalelwe kulo: | IShayina | |
| IZINTO ZOKUHLAZIYA | ISICELO | INDLELA YOKUHLOLA |
| Ukubukeka | Impuphu ecolekile | I-Organoleptic |
| Umbala | Impuphu ecolekile ensundu | Okubonakalayo |
| Iphunga Nokunambitha | Isici | I-Organoleptic |
| Ukuhlonza | Kufana nesampula ye-RS | I-HPTLC |
| Isilinganiso Sokukhipha | 4:1~20:1; UVincristine 98%min | |
| Ukuhlaziywa kwesihlungo | I-mesh engu-100% kuya ku-80 | I-USP39 <786> |
| Ukulahlekelwa ekomiseni | ≤ 5.0% | I-Euro.Ph.9.0 [2.5.12] |
| Umlotha Ophelele | ≤ 5.0% | I-Euro.Ph.9.0 [2.4.16] |
| I-Lead (Pb) | ≤ 3.0 mg/kg | I-Eur.Ph.9.0<2.2.58>ICP-MS |
| I-Arsenic (Njengoba) | ≤ 1.0 mg/kg | I-Eur.Ph.9.0<2.2.58>ICP-MS |
| I-Cadmium(Cd) | ≤ 1.0 mg/kg | I-Eur.Ph.9.0<2.2.58>ICP-MS |
| I-Mercury (Hg) | ≤ 0.1 mg/kg -Reg.EC629/2008 | I-Eur.Ph.9.0<2.2.58>ICP-MS |
| Insimbi enamandla | ≤ 10.0 mg/kg | I-Euro.Ph.9.0<2.4.8> |
| Izinsalela Zezinyibilikisi | Vumelana ne-Eur.ph. 9.0 <5,4 > kanye ne-EC European Directive 2009/32 | I-Euro.Ph.9.0<2.4.24> |
| Izinsalela Zezibulala-zinambuzane | Imithethonqubo Yokuhambisana (EC) No. 396/2005 kufaka phakathi izithasiselo kanye nokubuyekezwa okulandelayo Ukubhaliswa Okubhalisiwe 2008/839/CE | I-Gas Chromatography |
| Amagciwane e-aerobic (TAMC) | ≤10000 cfu/g | I-USP39 <61> |
| Imvubelo/Izikhunta (TAMC) | ≤1000 cfu/g | I-USP39 <61> |
| I-Escherichia coli: izifo ezithathelwanayo | Akukho ku-1g | I-USP39 <62> |
| I-Salmonella spp: | Akukho ku-25g | I-USP39 <62> |
| I-Staphylococcus aureus: izimpawu | Akukho ku-1g | |
| I-Listeria Monocytogenens | Akukho ku-25g | |
| Ama-Aflatoxin B1 | ≤ 5 ppb -Reg.EC 1881/2006 | I-USP39 <62> |
| Ama-Aflatoxin ∑ B1, B2, G1, G2 | ≤ 10 ppb -Reg.EC 1881/2006 | I-USP39 <62> |
Izici zomkhiqizo we-Vinca Rosea Extract Vincristine zingafaka:
Ubumsulwa obuphezulu:Imikhiqizo ye-Vincristine ivame ukuba nobumsulwa obuphezulu futhi ihambisana nezindinganiso eziqinile zokukhiqiza izidakamizwa ukuqinisekisa ubumsulwa nokuzinza komuthi.
Ukulandeleka komthombo:I-Vincristine ivame ukukhishwa esitshalweni se-Catharanthus roseus. Inqubo yayo yokukhiqiza iyalandelelwa futhi ihambisana nemininingwane yokuqoqwa kanye nokukhiqizwa kwezinto zokwelapha zezitshalo.
Ukuqina kwamakhemikhali:Njengenhlanganisela ye-alkaloid, i-vincristine inamandla amahle okuqina kwamakhemikhali futhi ifanele ukukhiqizwa kwemithi kanye nokugcinwa isikhathi eside.
Umsebenzi wokulwa nomdlavuza:Njengomuthi wokulwa nomdlavuza, i-vincristine inomsebenzi wokuvimbela ukukhula nokusabalala kwamaseli omdlavuza futhi ifanelekela ukwelapha umdlavuza ohlukahlukene.
Ukuqinisekiswa kwezokwelapha:I-Vincristine iqinisekiswe ngokwezokwelapha futhi isetshenziswa kabanzi kwezokwelapha, ngokusekelwa kwedatha yemiphumela yezokwelapha okuthembekile.
Lezi zici zomkhiqizo ziqokomisa ikhwalithi, umsebenzi, kanye nenani lezokwelapha le-vincristine njengomuthi obalulekile wokulwa nomdlavuza.
I-Vinca Rosea Extract I-Vincristine yaziwa kakhulu ngezicelo zayo zemithi ekwelapheni umdlavuza futhi ngokuvamile ayihlotshaniswa nezinzuzo zezempilo eziqondile zokusetshenziswa kwabathengi ngokujwayelekile. I-Vincristine, etholakala esitshalweni se-Vinca rosea, iwumuthi onamandla we-chemotherapy osetshenziselwa ukwelapha izinhlobo ezahlukene zomdlavuza, okuhlanganisa i-leukemia, i-lymphoma, kanye nezimila eziqinile. Isebenza ngokuphazamisa ukukhula kwamaseli omdlavuza.
Kubalulekile ukuqaphela ukuthi i-Vincristine umuthi onikezwa ngodokotela onikezwa ngaphansi kokuqondisa kochwepheshe bezempilo, futhi ukusetshenziswa kwawo kuhlotshaniswa nemiphumela emibi kanye nezingozi ezingaba khona. Ngakho-ke, ngokuvamile awuthengiswa noma usetshenziswe ngenxa yezinzuzo zawo zezempilo ngaphandle kwezindawo zomtholampilo.
Ukusetshenziswa okuningiliziwe kwe-Vinca Rosea Extract Vincristine kufaka phakathi:
Ukwelashwa Komdlavuza:I-Vincristine isetshenziswa kakhulu ekwelapheni izinhlobo ezahlukene zomdlavuza, okuhlanganisa i-leukemia, i-lymphoma, kanye nezimila eziqinile. Inikezwa njengengxenye yezindlela zokwelashwa ngamakhemikhali ukuvimbela ukukhula kwamaseli omdlavuza.
Ucwaningo Lwezokwelapha:Lesi siqeshana sisetshenziswa ocwaningweni lwemithi ekuthuthukiseni ukwelashwa okusha komdlavuza kanye nokutadisha indlela esebenza ngayo.
Ikhemistri Yezokwelapha:I-Vincristine isebenza njengenhlanganisela ewusizo emkhakheni we-chemistry yezokwelapha, inegalelo ekuthuthukisweni kwemithi emisha kanye nemithi yokwelapha.
I-Biotechnology:Lesi siqeshana singasetshenziswa ekusetshenzisweni kwe-biotechnology, njengokukhiqizwa kwezindlela zokulwa nomdlavuza kanye nezinhlelo zokulethwa kwemithi.
Izivivinyo Zemitholampilo:I-Vincristine ihilelekile ezivivinyweni zemitholampilo ukuze kuhlolwe ukusebenza kwayo ekwelapheni izinhlobo ezahlukene zomdlavuza kanye nokuphenya ukusetshenziswa okungenzeka kwezinye izimo zezokwelapha.
Ukwakhiwa Kwemithi:Lesi sithako sisetshenziswa ekwakhiweni kwemikhiqizo yemithi, okuhlanganisa izixazululo ezijovwayo kanye nezinye izinhlobo zomthamo wokwelapha umdlavuza.
Lezi zinhlelo zokusebenza zibonisa ukusetshenziswa okuhlukahlukene kwe-Vinca Rosea Extract Vincristine ekwelapheni umdlavuza, ucwaningo lwemithi, kanye nokuthuthukiswa kwemithi.
I-Vincristine iwumuthi onamandla we-chemotherapy, futhi ukusetshenziswa kwayo kungahlotshaniswa nemiphumela emibi eminingana engaba khona. Eminye yemiphumela emibi engaba khona ye-Vincristine powder ingafaka:
Ubuthi be-neuro:I-Vincristine ingadala umonakalo ohlelweni lwezinzwa oluseceleni, okuholela ezimpawini ezifana nokungazweli, ukuthuthumela, kanye nobuthakathaka emalungeni omzimba.
Imiphumela Yesisu:Imiphumela emibi evamile yesisu ingafaka isicanucanu, ukuhlanza, ukuqunjelwa, kanye nobuhlungu besisu.
Ukucindezelwa Komnkantsha Wamathambo:I-Vincristine ingacindezela umongo wamathambo, okuholela ekunciphiseni ukukhiqizwa kwamaseli egazi, okungase kuholele ekuntulekeni kwegazi, ukwanda kokungenwa izifo, kanye nokuthambekela kokopha.
Ukulahlekelwa Izinwele:Abanye abantu bangase balahlekelwe izinwele noma banciphe ngenxa yokwelashwa nge-Vincristine.
Ubuhlungu Bomhlathi:I-Vincristine ingabangela uhlobo oluthile lobuhlungu olwaziwa ngokuthi “i-vincristine-induced neuropathy-acute-onset,” olubonakala ngobuhlungu bomhlathi kanye nobunzima bokugwinya.
Eminye Imiphumela Engaba Khona:Eminye imiphumela emibi ingafaka ubuthakathaka bemisipha, izinguquko ekucindezelweni kwegazi, kanye nokusabela kokungezwani komzimba.
Kubalulekile ukuqaphela ukuthi uhlu olungenhla aluphelele, futhi ochwepheshe bezempilo kufanele baqaphe eduze abantu abathola i-Vincristine ukuthola noma yimiphi imiphumela emibi engaba khona. Imiphumela emibi ethile kanye nobunzima bayo kungahluka kumuntu nomuntu. Iziguli kufanele zixoxe ngemiphumela emibi engaba khona kanye nokukhathazeka nomhlinzeki wazo wezempilo ngaphambi kokuqala ukwelashwa kwe-Vincristine.
Ukupakisha Nesevisi
Ukupakisha
* Isikhathi Sokulethwa: Cishe izinsuku zokusebenza ezi-3-5 ngemuva kokukhokha kwakho.
* Iphakheji: Kuma-drum e-fiber anezikhwama ezimbili zepulasitiki ngaphakathi.
* Isisindo Esiphelele: 25kgs/isigubhu, Isisindo Esiphelele: 28kgs/isigubhu
* Usayizi Wesigubhu Nomthamo: ID42cm × H52cm, 0.08 m³/ Isigubhu
* Indawo Yokugcina: Igcinwe endaweni eyomile nepholile, gcina kude nokukhanya okunamandla nokushisa.
* Impilo Yeshelufu: Iminyaka emibili uma igcinwe kahle.
Ukuthunyelwa
* I-DHL Express, i-FEDEX, kanye ne-EMS ngamanani angaphansi kuka-50KG, ngokuvamile abizwa ngokuthi isevisi ye-DDU.
* Ukuthunyelwa ngemikhumbi ngamanani angaphezu kwama-500 kg; kanye nokuthunyelwa ngendiza ngama-50 kg ngaphezulu.
* Ngemikhiqizo enenani eliphezulu, sicela ukhethe ukuthunyelwa ngendiza kanye ne-DHL express ukuze kuphephe.
* Sicela uqinisekise ukuthi ungakwazi yini ukugcwalisa izimpahla uma zifika emasimini akho ngaphambi kokufaka i-oda. Kubathengi abavela eMexico, eTurkey, e-Italy, eRomania, eRussia, nakwezinye izindawo ezikude.
Izindlela Zokukhokha Nokulethwa
I-Express
Ngaphansi kwe-100kg, Izinsuku ezi-3-5
Isevisi yokungena emnyango kulula ukuyithatha izimpahla
Ngasolwandle
Ngaphezulu kwama-300kg, cishe izinsuku ezingama-30
Kudingeka umthengisi wezinsizakalo zokukhishwa kwemvume ochwepheshe
Ngomoya
100kg-1000kg, Izinsuku ezi-5-7
Kudingeka umthengisi wezinsizakalo zokuhlanza ochwepheshe kusukela esikhumulweni sezindiza kuya esikhumulweni sezindiza
Imininingwane Yokukhiqiza (Ishadi Lokugeleza)
1. Ukuthola Nokuvuna
2. Ukukhipha
3. Ukugxila Nokuhlanzwa
4. Ukomisa
5. Ukulinganisa
6. Ukulawulwa Kwekhwalithi
7. Ukupakisha 8. Ukusatshalaliswa
Isitifiketi
It iqinisekiswe yizitifiketi ze-ISO, HALAL, kanye ne-KOSHER.
