I-Corydalis Extract Tetrahydropalmatine (dl-THP)

Igama Lomkhiqizo:I-Tetrahydropalmatine
Inombolo ye-CAS:6024-85-7
Ifomula ye-molecular:I-C21H26NO4
Ukucaciswa:I-Tetrahydropalmatine ≥ 98% HPLC
Ukubukeka:Okuphuzi okukhanyayo kuya kumpushana oyikristalu emhlophe, engenaphunga, ukunambitheka okubabayo kancane
Isici Esiyinhloko:Umphumela we-analgesic onokulutha okuncane

Thumela i-imeyili kithi

Imininingwane Yomkhiqizo

Omaka bomkhiqizo

Isingeniso Somkhiqizo

I-Tetrahydropalmatine (THP), eyaziwa nangokuthi i-dl-THP, i-Corydalin hydrochloride, noma i-Corydalin Tube Extract, iyinhlanganisela ehlukaniswa njenge-alkaloid ye-isoquinoline. Ikhishwa ku-tuber yesitshalo saseShayina i-Corydalis yanhusuo. I-THP into eyikristalu engenambala noma ephuzi ngokuphaphathekile enokunambitheka okubabayo nendawo encibilikayo engu-147-149°C. Ayincibiliki emanzini kodwa incibilika kakhulu ku-ether, i-chloroform, ne-ethanol. I-hydrochloride yayo ne-sulfate salts iyancibilika emanzini.
I-THP iye yafundelwa imiphumela ehlukahlukene yemithi, okuhlanganisa i-analgesic, i-anesthetic, i-neuroprotective, i-antiplatelet aggregation, i-antiulcer, i-antitumor, ne-anti-addiction properties. Kukholakala ukuthi isebenzisa imiphumela yayo ye-analgesic ngokumodela umsebenzi ophakathi we-dopamine receptor futhi ibonise amandla okuvikela ama-neurons ekulimaleni kwe-ischemic. Ukwengeza, i-THP ibonise imiphumela ye-antiplatelet aggregation futhi iphenywe amandla ayo ekwelapheni izilonda, ukuvimbela ukukhula kwamangqamuzana e-tumor, kanye nokusiza ekuluthweni kwezidakamizwa.
Sekukonke, i-Tetrahydropalmatine (dl-THP) iyinhlanganisela enezinto ezehlukene zemithi futhi ibe yisihloko socwaningo olunzulu ngezicelo zayo zokwelapha ezingaba khona. Ukuze uthole olunye ulwazi xhumana nayegrace@biowaycn.com.

Isici

Nazi izici zomkhiqizo we-Tetrahydropalmatine (THP) kanye nezinzuzo zabo zezempilo:
1. Izici ze-Analgesic:I-THP ibonisa imiphumela ye-analgesic ngokumodela umsebenzi omaphakathi we-dopamine receptor, inikeze ukukhululeka kobuhlungu ngaphandle kwamandla abalulekile okulutha.
2. I-Neuroprotective Effects:I-THP ibonise amandla okuvikela ama-neurons ekulimaleni kwe-ischemic, ekwehliseni i-apoptosis ye-neuronal, kanye nokwehlisa amazinga e-glutamate ebuchosheni, okungase kube nomthelela ezinhlelweni zayo ze-neuroprotective.
3. I-Antiplatelet Aggregation:I-THP itholwe ukuthi ivimbela ukuhlangana kweplatelet, okungenzeka yehlise ubungozi bokwakheka kwehlule legazi kanye nemicimbi yenhliziyo nemithambo yegazi ehlobene.
4. Ukwesekwa Kwempilo Yesisu:I-THP ibonise imiphumela yokulwa nesilonda futhi ingase isize ekwehliseni ukukhishwa kwe-asidi esiswini, inikeze ukukhululeka ezilonda zesisu nezimo ezihlobene nazo.
5. Umsebenzi Ongaba khona we-Antitumor:I-THP ibonise imiphumela ye-cytotoxic kumaseli wesimila, iphakamisa indima engaba khona ekuvimbeleni ukukhula kwesimila.
6. Izici Zokulwa Nomlutha:I-THP iye yafundelwa amandla ayo okunciphisa izimpawu zokuhoxa ezihambisana ne-opioid kanye nokulutheka okuvusa inkanuko, enikeza isithembiso ekwelashweni kokulutheka kanye nokuvimbela ukuphinda kuqubuke.
Lezi zici zigqamisa izinzuzo zezempilo ezahlukahlukene kanye nezinhlelo zokwelapha ezingaba khona ze-Tetrahydropalmatine (THP).

Incazelo Yezitshalo

I-Tetrahydropydalin (dl-THP) ingeye-alkaloids ye-isoquinoline futhi iyi-alkaloid, ikakhulukazi ohlotsheni lwe-Corydalis lucidum (Yan Hu Suo), kodwa nakwezinye izitshalo ezifana ne-Stephania rotunda. Lezi zitshalo zinokusetshenziswa kwendabuko emithini yamakhambi yaseShayina.I-Corydalis isitshalo esihlala isikhathi eside se-herbaceous, esingama-10 kuya ku-20 cm ubude, sinezilimo eziyizigaxa eziyindilinga. Iziqu zayo ezingaphezulu komhlaba zifushane futhi zizacile, zinesilinganiso ngaphezu kwesisekelo. Amaqabunga e-basal namaqabunga e-cauline afana ngesimo, aneziqu; amaqabunga e-cauline ayashintshana, anamaqabunga ama-2 no-3 ahlanganisiwe. Iqabunga lesibili livame ukuhlukana ngokungaphelele futhi lijule ngokujulile. Amaqabunga amancane ane-oval, i-oval noma i-oval. Umugqa, cishe u-2 cm ubude, une-apex ecijile noma ecijile kanye nemiphetho ehlanzekile. I-inflorescence yayo imise okwe-raceme, inamaqabunga abulalayo noma aphikisanayo; ama-bracts ane-lanceolate ebanzi; izimbali zibomvu-nsomi futhi zikhula zivundlile kuma-pedicels azacile, angaba ngu-6 mm ubude; i-calyx iwa ekuqaleni; amacembe angu-4 nama-whorl angaphandle angu-2 Amasegimenti makhudlwana, anomphetho opinki kanye nendawo ephakathi nendawo ngokunsomi. Kunengxenye eyodwa engenhla, futhi umsila ufinyelela ku-spur ende. Ubude be-spur bubalelwa cishe ingxenye yobude obuphelele. Amasegimenti ama-2 angaphakathi mancane kunamasegimenti ama-2 angaphandle. Ingxenye engenhla inombala oluhlaza okwesibhakabhaka-onsomi futhi iphulukisiwe, futhi ingxenye engezansi inombala opinki; Ama-stamens angu-6, futhi imicu ixhunywe ibe izinyanda ezimbili, ngayinye inama-anther angu-3; i-ovary i-flat-cylindrical, isitayela sifushane futhi sincane, futhi inhlamba i-2, njengovemvane oluncane. Isithelo saso siyi-capsule. I-Corydalis ikhiqizwa kakhulu ezintabeni noma ezindaweni ezinotshani. Izindawo ezikhiqizayo eziyinhloko zifaka iZhejiang, iHebei, iShandong, iJiangsu, nezinye izindawo.

Ukucaciswa

Ukuhlaziya	Ukucaciswa
Isivivinyo	I-Tetrahydropalmatine ≥98%
Ukubukeka	Impushana ephuzi ekhanyayo ukuya kuPhoda omhlophe
Umlotha	≤0.5%
Umswakama	≤5.0%
Izibulala-zinambuzane	Okubi
Izinsimbi ezinzima	≤10ppm
Pb	≤2.0ppm
As	≤2.0ppm
Iphunga	Isici
Usayizi wezinhlayiya	100% ngokusebenzisa i-80 mesh
I-Microbiological :
Isamba samagciwane	≤1000cfu/g
Isikhunta	≤100cfu/g
Salmgosella	Okubi
Coli	Okubi

Isicelo

Nazi izimboni zokusetshenziswa komkhiqizo ze-Tetrahydropalmatine (THP):
1. Ezemithi:I-THP isetshenziswa embonini yezemithi ekwenzeni imithi yokulawula ubuhlungu kanye nezidakamizwa ze-neuroprotective.
2. I-Nutraceuticals:I-THP isetshenziswa embonini yezomsoco ukuze kwenziwe izithasiselo eziqondise ekudambiseni ubuhlungu kanye nokwesekwa kwezempilo kwesisu.
3. I-Biotechnology:I-THP ithola izinhlelo zokusebenza ku-biotechnology zokucwaninga ngemithi ye-antiplatelet kanye nesengezo esingaba khona sokwelashwa komdlavuza.
4. Ukunakekelwa kwezempilo:I-THP ifakwe emikhiqizweni yokunakekelwa kwezempilo yokulawula ukulutheka kanye nezimpawu zokuhoxa ezihambisana ne-opioid kanye nokusetshenziswa okushukumisayo.
5. Izimonyo:I-THP ihlolisiswa ku-cosmeceuticals yezempilo yesikhumba engaba khona kanye nezicelo zokulwa nokuvuvukala.
Lezi zimboni zibonisa ukusetshenziswa okuhlukahlukene okungenzeka kwe-Tetrahydropalmatine (THP) ekuthuthukisweni kwemikhiqizo ehlukahlukene nezimo zocwaningo.

Imininingwane Yokukhiqiza

Imikhiqizo yethu yakhiwe kusetshenziswa izinyathelo eziqinile zokulawula ikhwalithi futhi ithobela amazinga aphezulu ezinqubo zokukhiqiza. Sibeka phambili ukuphepha nekhwalithi yomkhiqizo wethu, siqinisekisa ukuthi uhlangabezana nezidingo zokulawula kanye nezitifiketi zomkhakha. Lokhu kuzibophezela kwikhwalithi kuhloswe ukusungula ukwethembana nokwethembeka ekuthembekeni komkhiqizo wethu. Inqubo yokukhiqiza ejwayelekile imi kanje:

Ukupakisha kanye Nesevisi

Isitoreji:Gcina endaweni epholile, eyomile, nehlanzekile, Vikela kumswakama nokukhanya okuqondile.
Iphakheji Yenqwaba:20~25kg/isigubhu.
Isikhathi esiholayo:Izinsuku ezingu-7 ngemva kwe-oda lakho.
Impilo Yeshelufu:iminyaka engu-2.
Phawula:Ukucaciswa okwenziwe ngezifiso kungafinyelelwa.