I-Pure Rotundine Powder(l-tetrahydropalmatine，l-THP) Isithombe Esifakiwe

I-Rotundine Powder ehlanzekile(l-tetrahydropalmatine,l-THP)

Amanye Amagama:I-L-Tetrahydropalmatine
Umthombo Wesitshalo:Stephania tetrandra noma Corydalis yanhusuo
Inombolo ye-CAS:10097-84-4
Ukucaciswa:98%imizuzu
MW:355.43
MF:I-C21H25NO4
I-Melting Point:140-1°C
Izinga lokushisa lesitoreji.:I-Hygroscopic, Isiqandisi, ngaphansi komkhathi ongasebenzi
Ukunyibilika:I-Chloroform (Kancane), i-Methanol (Kancane)
Umbala:Impushana Eqinile Emhlophe ukuya Kokumhlophe

Thumela i-imeyili kithi

Imininingwane Yomkhiqizo

Omaka bomkhiqizo

Isingeniso Somkhiqizo

I-Rotundine, eyaziwa nangokuthi i-l-tetrahydropalmatine (l-THP), iyinhlanganisela enezakhiwo ze-pharmacological ezithinta isimiso sezinzwa esiyinhloko kanye nesistimu yenhliziyo. Kuye kwabikwa ukuthi kune-analgesic, sedative, hypnotic, nemiphumela ye-anxiolytic. Ukwengeza, kuboniswe ukuthi kunemiphumela yokuvikela ekulimazeni kobuchopho kanye ne-myocardial ischemia-reperfusion. I-Rotundine yaziwa futhi ngamandla ayo okubuyisela emuva ukumelana nezidakamizwa eziningi kumaseli omdlavuza kanye nezakhiwo zayo zokuvimba isiteshi se-calcium.
Ingatholakala ezigabeni ze-Stephania tetrandra kanye ne-Corydalis yanhusuo, noma ngezindlela zokuhlanganisa amakhemikhali. Kuhlanganiswe kusuka ku-tetrahydropalmatine ngokunciphisa, ukuqhekeka, kanye nokusabela kwe-alkalization. I-tetrahydropalmatine ene-iodine ingakhiqizwa kusukela ku-tetrahydropalmatine ngokusebenzisa i-alkalization kanye ne-oxidation ukuze kuhlanganiswe okuphindaphindiwe.
Ku-pharmacokinetics, i-Rotundine imuncwa kahle ngemva kokuphathwa ngomlomo futhi isatshalaliswa ngokuyinhloko kuzicubu ze-adipose, ilandelwa amaphaphu, isibindi, nezinso. Ikhishwa kakhulu ngezinso. Ucwaningo kumagundane kanye nonogwaja lubonise ukuthi i-Rotundine ingangena kusivimbeli segazi nobuchopho futhi ingene ezicutshini zobuchopho, nokugxila kobuchopho okuphansi kunokugxila kwegazi ngemva kwamahora ama-2.
Ngemiphumela emibi, i-Rotundine ingase ibangele ukozela, isiyezi, ukukhathala, isicanucanu, kanye nokushaqeka kwe-allergic ngezikhathi ezithile. Izinyathelo zokuqapha zihlanganisa ukugwema ukusetshenziswa kwabesifazane abakhulelwe nabancelisayo, ukuqaphela ukuthi kungenzeka ukubekezelela ukusetshenziswa isikhathi eside, kanye nokusebenzisa ukuqapha lapho uphatha ngokuhlanganyela nezinciphiso zesimiso sezinzwa esimaphakathi, nokulungiswa komthamo okufanele uma kunesidingo.
Kafushane, i-Rotundine iyinhlanganisela enemiphumela ehlukahlukene yezokwelapha, futhi izakhiwo zayo ziyenza ibe isihloko esithakaselwayo ocwaningweni oluhlukahlukene, okuhlanganisa ukuphathwa kobuhlungu, impilo yenhliziyo nemithambo yegazi, kanye nokwelashwa komdlavuza. Ukuze uthole olunye ulwazi xhumana nayegrace@biowaycn.com.

Isici

Ukunciphisa ubuhlungu:I-Rotundine iboniswe ukuthi inezici ze-analgesic, okwenza iphumelele ekunciphiseni ubuhlungu nokungakhululeki.
Imiphumela elwa nokuvuvukala:I-Rotundine ibonise izakhiwo zokulwa nokuvuvukala, ezingasiza ekunciphiseni ukuvuvukala kanye nezimpawu ezihambisanayo.
Ukuphumula kanye ne-sedation:I-Rotundine isetshenziselwe ukukhuthaza ukuphumula kanye ne-sedation, okwenza kube yinzuzo ekulawuleni ukucindezeleka nokukhathazeka.
Umsebenzi we-Antioxidant:I-Rotundine itholakale ibonisa imiphumela ye-antioxidant, engasiza ukuvikela amangqamuzana emonakalweni obangelwa ama-radicals mahhala.
Amathuba okwelashwa kokulutheka:Olunye ucwaningo lubonisa ukuthi i-Rotundine ingase ibe namandla okulawula ukulutheka kanye nezimpawu zokuhoxa, ikakhulukazi ekuncikeni kwe-opioid.
Izinzuzo zesisu:I-Rotundine iye yafundelwa amandla ayo okunciphisa izinkinga zesisu, njengama-spasms nokungakhululeki.

Ukucaciswa

Ukuhlaziya	Ukucaciswa
Isivivinyo	I-Tetrahydropalmatine ≥98%
Ukubukeka	Impushana ephuzi ekhanyayo ukuya kuPhoda omhlophe
Umlotha	≤0.5%
Umswakama	≤5.0%
Izibulala-zinambuzane	Okubi
Izinsimbi ezinzima	≤10ppm
Pb	≤2.0ppm
As	≤2.0ppm
Iphunga	Isici
Usayizi wezinhlayiya	100% ngokusebenzisa i-80 mesh
I-Microbiological :
Isamba samagciwane	≤1000cfu/g
Isikhunta	≤100cfu/g
Salmgosella	Okubi
Coli	Okubi

Isicelo

I-Rotundine inezicelo ezimbonini ezimbalwa, okuhlanganisa:
Imboni Yezemithi:I-Rotundine isetshenziswa embonini yezemithi ngenxa yezakhiwo zayo ezingaba zokudambisa izinhlungu, zokudambisa, kanye ne-anxiolytic. Ingase ifakwe emithini yokulawula ubuhlungu nokukhulula ukukhathazeka.
Ukunakekelwa Kwempilo Nokuphila:Ngenxa yezinzuzo zayo zezempilo ezibikiwe, i-Rotundine ingase isetshenziselwe ukunakekelwa kwezempilo kanye nemikhiqizo yokuphila kahle okuhloswe ngayo ukukhuthaza ukuphumula nokulawula ubuhlungu.
Ucwaningo Nokuthuthukiswa:I-Rotundine inentshisekelo emizamweni yocwaningo nentuthuko egxile empilweni yenhliziyo nemithambo yegazi, ukwelashwa komdlavuza, nezimo zemizwa ngenxa yemiphumela yayo ebikiwe kulezi zinhlelo.
I-Nutraceuticals:Kukhona amandla okufakwa kwe-Rotundine emikhiqizweni ye-nutraceutical eyenzelwe ukusekela impilo yonke kanye nokuphila kahle.
Kubalulekile ukuqaphela ukuthi ukusetshenziswa okukhethekile kwe-Rotundine kungase kuhluke ngokusekelwe ekugunyazweni kokulawula kanye nocwaningo oluqhubekayo embonini ngayinye.

Imininingwane Yokukhiqiza

Imikhiqizo yethu yakhiwe kusetshenziswa izinyathelo eziqinile zokulawula ikhwalithi futhi ithobela amazinga aphezulu ezinqubo zokukhiqiza. Sibeka phambili ukuphepha nekhwalithi yomkhiqizo wethu, siqinisekisa ukuthi uhlangabezana nezidingo zokulawula kanye nezitifiketi zomkhakha. Lokhu kuzibophezela kwikhwalithi kuhloswe ukusungula ukwethembana nokwethembeka ekuthembekeni komkhiqizo wethu. Inqubo yokukhiqiza ejwayelekile imi kanje:

Ukupakisha kanye Nesevisi

Isitoreji:Gcina endaweni epholile, eyomile, nehlanzekile, Vikela kumswakama nokukhanya okuqondile.
Iphakheji Yenqwaba:20~25kg/isigubhu.
Isikhathi esiholayo:Izinsuku ezingu-7 ngemva kwe-oda lakho.
Impilo Yeshelufu:iminyaka engu-2.
Phawula:Ukucaciswa okwenziwe ngezifiso kungafinyelelwa.