I-sinomenine hydrochloride powder
I-Sinomenine Hydrochloride iyindlela yamakhemikhali ethathwe kwisitshalo i-sinomenium acutum, evame ukutholakala eMpumalanga Asia. Kuyinto i-alkaloid eye yasetshenziswa ngokwesiko emithini yesiShayina yezakhiwo zayo zokulwa nokuvuvukala kanye ne-analgesic. Ifomu le-hydrochloride ngusawoti othuthukisa ukuqina kwe-compound nokuqina, okwenza kube lula ukusetshenziswa kwezemithi.
Sinomenine Hydrochloride has been studied for its potential therapeutic effects in treating conditions such as rheumatoid arthritis, due to its ability to modulate the immune system and reduce inflammation. Isebenza ngokuvimbela ukukhiqizwa kwama-cytokines wokuvuvukala kwama-pro-inflammatory kanye nabanye abalamuli ababambe iqhaza ekuphenduleni kokuvuvukala.
Ngaphezu kwemiphumela yayo yokulwa nokuvuvukala kanye ne-analgesic, i-sinomenine hydrochloride ibuye ikhombise amathuba okuba yi-neuroprotection, anti-fibrosis, kanye nemisebenzi ye-anti-Tumos ezifundweni ezahlukahlukene zokubhala.
Igama elisemthethweni: (9a, 13a, 14a) -7,8-Didehydro-4,8-Didehydro-4-3,7-DIMETHOXY-6-Methyl-Morphinan-6-One, Monohydrochlor-6-One, Monohydrochloride
Inombolo ye-CAS: 6080-33-7
Izimpawu: Cucoline NSC 76021
Ifomula ye-molecular: C19h23No4 • HLCE
Isisindo sefomula: 365.9
Ukumsulwa: ≥98% i-crystalline iqinile
I-Solubity (Funda Ngokuhlukahluka Kwe-Solubity)
DMF: 30 mg / ml
DMSO: 30 MG / ML
I-Ethanol: 5 mg / ml
PBS (PH 7.2): 5 MG / ML
Imvelaphi: Plat / Sinomenium Acutum
Ukuthumela Nokugcina Imininingwane:
Isitoreji-° C C
Ukuthumela: Ukushisa kwegumbi
Ukuqina: ≥ iminyaka emi-4
| Into yendaba | Ukucacisa | Umphumela |
| Assay (HPLC) | 98.0% | 98.12% |
| Ukubonakala | umhlophe we-powder | Qhubelelayo |
| Usayizi wezinhlayiyana | 98% nge-80mesh | Qhubelelayo |
| Iphunga | -Yisimilo | Qhubelelayo |
| Ukuzwa emlonyeni | -Yisimilo | Qhubelelayo |
| Izici Zomzimba | ||
| Ukulahleka kokuwomile | ≤0.5% | 0.38% |
| Umlotha | ≤0.5% | 0.46% |
| Izinsimbi ezisindayo | ||
| Izinsimbi ezisindayo (njenge-PB) | Amazinga e-USP (<10ppm) | <10ppm |
| I-Arsenic (as) | ≤2ppm | 0.78ppp |
| Ukuhola (PB) | ≤2ppm | 1.13PPM |
| I-Cadmium (CD) | ≤LPPPM | 0.36ppm |
| UMebiya (Hg) | ≤0.1ppm | 0.01ppm |
| Izinsalela zokubulala izinambuzane | Engatholakali | Engatholakali |
| Inani eliphelele | I-NMT 10000CFU / G | I-680 CFU / G |
| Ingqikithi yemvubelo & isikhunta | I-NMT 100CFU / G | I-87 CFU / g |
| E.coli | Nmt 30cFU / g | I-10 cfu / g |
| Salmonella | -Phikisayo | -Phikisayo |
| Ukugcina | Avumelanise ukufakwa kwebhizinisi | |
Imiphumela eyinhloko yeSininomenine Hydrocloworide ifaka:
(1) I-Anti-inflammatory: Yehlisa ukuvuvukala.
(2) I-analgesic: inikeza impumuzo yobuhlungu.
(3) I-immunosupprespitive: icindezela umsebenzi wesistimu yokuvikelwa komzimba.
(4) I-Anti-Rheumatic: Iphatha i-rheumatoid arthritis.
(5) I-NeuroPRECTION: Ivikela amaseli ezinzwa ekulimaleni.
(6) Anti-FIBROTOT: Kuvimbela noma kunciphise i-fibrosis yezicubu.
I-sinomenine hydrochloride isetshenziswa ikakhulukazi kulezi zindawo ezilandelayo:
(1) I-Rheumatology: Ukwelashwa kwe-rheumatoid arthritis.
(2) Ukuphathwa kobuhlungu: Ukulwa nobuhlungu obungamahlalakhona.
(3) Ukulwa nokuvuvukala: ukuncishiswa kokuvuvukala.
(4) I-Immunomodation: Ukuguqulwa kwamasosha omzimba.
(5) I-Neuroprotection: Ukusetshenziswa okungenzeka ngezindlela zokwelapha ezi-inuroprotute.
Inqubo yokukhiqiza yeSinromenine Hydrocloride Powder ingafushaniswa kanjena:
Ukulungiselela imihlambi:Ukuhlanza nokumisa impahla yezitshalo eluhlaza.
Ukukhishwa:Kusetshenziswa ama-solvents njenge-ethanol ukukhipha i-sinomenine kusuka ezintweni zezitshalo.
Ukugxila:Ukuphuma ku-solvent ukugxilisa okuqukethwe kwe-sinomen.
I-Alkalization:Ukulungisa i-PH ukuguqula i-sinomenine kwifomu laso usawoti.
Ukukhishwa okuwuketshezi owuketshezi:Ukuhlanza ngezinto eziphilayo ezifana ne-anisole noma i-1-heptanol.
Ukugeza:Ukugeza okunamanzi ukususa ukungcola kanye nokulandela izindonga.
I-Acidization:Ukunciphisa i-PH ukucacisa i-sinamenine hydrochloride.
I-Crystallization:Kwakha amakristalu eSinomenine Hydrocloworide.
Ukwahlukana:I-centrifuging noma ukuhlunga ukuhlukanisa amakristalu kwikhambi.
Ukomisa:Isusa umswakama osele kusuka kumakristalu.
Milling:Ukugaya amakristalu omisiwe ku-powder enhle.
Kusihlwa:Ukuqinisekisa ukusatshalaliswa kosayizi abafanayo.
Ikhwalithi yokulawula:Ukuhlola ubumsulwa, ukugxila, kanye namazinga e-microbiological.
Ukupakishwa:Ipakisha eyinyumba futhi evikelekile yokusatshalaliswa.
Isitoreji: Gcina endaweni epholile, eyomile, nehlanzekile, ukuvikela kumswakama nokukhanya okuqondile.
Iphakheji le-Bulk: 25kg / Drum.
Isikhathi sokuhola: izinsuku eziyi-7 ngemuva kwe-oda lakho.
Impilo yesheluphelo: iminyaka emi-2.
Ukuphawula: Ukucaciswa okwenziwe ngezifiso nakho kungatholakala.
Khama
Ngaphansi kwe-100kg, 3-5days
Umnyango wesevisi emnyango kulula ukukhetha izimpahla
Ngolwandle
Ngaphezulu300kg, cishe izinsuku ezingama-30
IPort to Port Service Professional Sholearance Broker edingekayo
Ngomoya
I-100kg-1000kg, 5-7days
Isikhumulo sezindiza esikhumulweni sezindiza i-Professional Professional Professional Broker edingekayo
I-Bioway Organic isizuze i-USDA ne-EU Organic, BRC, ISO, Halal, Kosher, Nezitifiketi ze-HACCP.
