I-Sinomenine Hydrochloride Powder
I-Sinomenine Hydrochloride iyinhlanganisela yamakhemikhali etholakala esitshalweni i-Sinomenium acutum, esivame ukutholakala eMpumalanga Asia. Iyi-alkaloid ebilokhu isetshenziswa kwezokwelapha zaseShayina ngenxa yezakhiwo zayo zokulwa nokuvuvukala kanye nezokudambisa ubuhlungu. Uhlobo lwe-hydrochloride luwusawoti othuthukisa ukuncibilika nokuqina kwenhlanganisela, okwenza ifaneleke kakhulu ukusetshenziswa kwemithi.
I-Sinomenine Hydrochloride iye yacwaningwa ngemiphumela yayo yokwelapha engaba khona ekwelapheni izimo ezifana ne-rheumatoid arthritis, ngenxa yekhono layo lokuguqula isimiso somzimba sokuzivikela kanye nokunciphisa ukuvuvukala. Isebenza ngokuvimbela ukukhiqizwa kwama-cytokine abangela ukuvuvukala kanye nezinye izinto ezihilelekile empendulweni yokuvuvukala.
Ngaphezu kwemiphumela yayo yokulwa nokuvuvukala kanye neyokudambisa ubuhlungu, i-Sinomenine Hydrochloride iphinde yabonisa amandla emisebenzini yokuvikela izinzwa, ukulwa ne-fibrosis, kanye nokulwa nomdlavuza ezifundweni ezahlukahlukene zangaphambi kokwelashwa.
Igama Elisemthethweni: (9a,13a,14a)-7,8-didehydro-4-hydroxy-3,7-dimethoxy-17-methyl-morphinan-6-one, i-monohydrochloride
Inombolo ye-CAS: 6080-33-7
Amagama afanayo：Cucoline NSC 76021
Ifomula Yamamolekyuli： C19H23NO4 • HCl
Isisindo sefomula: 365.9
Ubumsulwa: ≥98% I-crystalline eqinile
Ukuncibilika (Funda ngokuhlukahluka kokuncibilika)
I-DMF: 30 mg/ml
I-DMSO: 30 mg/ml
I-ethanol: 5 mg/ml
I-PBS (pH 7.2): 5 mg/ml
Umsuka:Isitshalo/Sinomenium acutum
Ulwazi Lokuthumela Nokugcina Izinto:
Isitoreji -20°C
Ukuthumela: Izinga Lokushisa Legumbi
Ukuzinza: ≥ iminyaka emi-4
| Into | Imininingwane | Umphumela |
| Ukuhlolwa (i-HPLC) | 98.0% | 98.12% |
| Ukubukeka | Impuphu emhlophe | Imithetho |
| Usayizi Wezinhlayiya | 98% kuya ku-80mesh | Imithetho |
| Iphunga | Isici | Imithetho |
| Ukunambitha | Isici | Imithetho |
| Izici Zomzimba | ||
| Ukulahlekelwa Kokomisa | ≤0.5% | 0.38% |
| Umlotha | ≤0.5% | 0.46% |
| Izinsimbi ezisindayo | ||
| Izinsimbi ezisindayo (njenge-Pb) | Izindinganiso ze-USP (<10ppm) | <10ppm |
| I-Arsenic (Njengoba) | ≤2ppm | 0.78ppm |
| I-Lead (Pb) | ≤2ppm | 1.13ppm |
| I-Cadmium(Cd) | ≤lpm | 0.36ppm |
| I-Mercary (Hg) | ≤0.1ppm | 0.01ppm |
| Insalela Yezibulala-zinambuzane | Akutholakalanga | Akutholakalanga |
| Inani Eliphelele Lepuleti | I-NMT 10000cfu/g | 680 cfu/g |
| Imvubelo Ephelele kanye Nokubumba | I-NMT 100cfu/g | 87 cfu/g |
| I-E.Coli | I-NMT 30cfu/g | 10 cfu/g |
| I-Salmonella | Okubi | Okubi |
| Isiphetho | Kuvumelana Nezindinganiso Zebhizinisi | |
Imiphumela eyinhloko ye-Sinomenine Hydrochloride ifaka:
(1) Ilwa nokuvuvukala: Yehlisa ukuvuvukala.
(2) I-Analgesic: Inikeza ukukhululeka ebuhlungwini.
(3) Ukucindezela amasosha omzimba: Ukucindezela umsebenzi wamasosha omzimba.
(4) Ilwa namathambo: Yelapha isifo samathambo esibizwa ngokuthi i-rheumatoid arthritis.
(5) Ukuvikela izinzwa: Kuvikela amangqamuzana ezinzwa ekulimaleni.
(6) Ilwa ne-fibrotic: Ivimbela noma yehlisa i-fibrosis yezicubu.
I-Sinomenine Hydrochloride isetshenziswa kakhulu kulezi zindawo ezilandelayo:
(1) I-Rheumatology: Ukwelashwa kwe-rheumatoid arthritis.
(2) Ukuphathwa Kobuhlungu: Ukunciphisa ubuhlungu obungapheli.
(3) Ukulwa nokuvuvukala: Ukunciphisa ukuvuvukala.
(4) Ukuguqulwa kwamasosha omzimba: Ukuguqulwa kwamasosha omzimba.
(5) Ukuvikela izinzwa: Ukusetshenziswa okungenzeka ekwelashweni kokuvikela izinzwa.
Inqubo yokukhiqiza i-Sinomenine Hydrochloride Powder ingafingqwa kanje:
Ukulungiselela Amakhambi:Ukuhlanza nokomisa izinto zesitshalo ezingavuthiwe.
Ukukhipha:Ukusebenzisa izinyibilikisi ezifana ne-ethanol ukukhipha i-sinomenine ezintweni zesitshalo.
Ukugxila:Ukuhwamuka kwesinyibilikisi ukuze kugxilwe okuqukethwe yi-sinomenine.
Ukwenziwa kwe-alkalization:Ukulungisa i-pH ukuze kuguqulwe i-sinomenine ibe yisimo sayo sikasawoti.
Ukukhishwa Koketshezi Oluyi-Liquid:Ukuhlanza ngezithako eziphilayo ezifana ne-anisole noma i-1-heptanol.
Ukugeza:Ukuwasha ngamanzi ukuze kususwe ukungcola kanye neminonjana yesinyibilikisi.
Ukwenziwa kwe-asidi:Ukunciphisa i-pH ukuze kusheshiswe i-sinomenine hydrochloride.
Ukwakheka kwekristalu:Ukwakha amakristalu e-sinomenine hydrochloride.
Ukuhlukana:Ukuhlunga noma ukuhlunga ukuze kuhlukaniswe amakristalu nesisombululo.
Ukomisa:Ukususa umswakama osele kumakristalu.
Ukugaya:Ukugaya amakristalu omisiwe abe yimpuphu ecolekile.
Ukuhluma:Ukuqinisekisa ukusatshalaliswa kosayizi wezinhlayiya ezifanayo.
Ikhwalithi yokulawula:Ukuhlolwa kobumsulwa, ukuhlushwa, kanye nezindinganiso zezinto eziphilayo.
Ukupakisha:Ukupakishwa okuhlanzekile nokuphephile ukuze kusatshalaliswe.
Indawo Yokugcina: Gcina endaweni epholile, eyomile, nehlanzekile, Vikela emswakama nasekukhanyeni okuqondile.
Iphakheji Elikhulu: 25kg/isigubhu.
Isikhathi Sokuhola: Izinsuku eziyi-7 ngemuva kwe-oda lakho.
Impilo Yeshelufu: Iminyaka emi-2.
Phawula: Ukucaciswa okwenziwe ngezifiso nakho kungafinyelelwa.
I-Express
Ngaphansi kwe-100kg, izinsuku ezi-3-5
Isevisi yokungena emnyango kulula ukuyithatha izimpahla
Ngasolwandle
Ngaphezulu kwama-300kg, cishe izinsuku ezingama-30
Kudingeka umthengisi wezinsizakalo zokukhishwa kwemvume ochwepheshe
Ngomoya
100kg-1000kg, Izinsuku ezi-5-7
Kudingeka umthengisi wezinsizakalo zokuhlanza ochwepheshe kusukela esikhumulweni sezindiza kuya esikhumulweni sezindiza
I-Bioway Organic ithole izitifiketi ze-USDA kanye ne-EU organic, i-BRC, i-ISO, i-HALAL, i-KOSHER, kanye ne-HACCP.
